Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Comparison of Rabbit Antithymocyte Globulin (R-ATG) and Jurkat Cell-Reactive Anti-T Lymphocyte Globulin (ATG-F) as a First-line Treatment for Children with Aplastic Anemia

    ... globulin (R-ATG) and Jurkat cell-reactive anti- T lymphocyte globulin (ATG-F) in the treatment of childhood aplastic ... infection control. Absolute counts of peripheral blood lymphocyte (ALC) in various time points were dynamically measured after ATG ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Host immunity affects survival in myelodysplastic syndromes: Independent prognostic value of the absolute lymphocyte count.

    ... prognostic significance of the peripheral blood absolute lymphocyte count (ALC) has been carefully examined in lymphoid ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes

    ... more effective. Adjusting the timing and dose of donor lymphocyte infusion reduces the risk of graft-versus-host disease without jeopardizing the graft-versus-leukaemia effect of donor lymphocyte infusion. SUMMARY: Allogeneic haematopoietic stem cell ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. A Marked Decrease in CD4-Positive Lymphocytes at the Onset of Hepatitis in a Patient With Hepatitis-Associated Aplastic Anemia.

    ... especially CD4 T-lymphocytopenia. Although the total lymphocyte counts rose as the patient recovered from hepatitis, this was ... treated with immunosuppressive therapy, which normalized the lymphocyte subset proportions. T-cell subsets analysis at the onset of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

    ... deficient progenitor cells, a novel T lymphocyte enrichment culture assay with proaerolysin selection to expand ... T lymphocytes and 3 of them were detected only after T lymphocyte enrichment in proaerolysin selection. PIG-A mutation analyses on 3 ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Aplastic Anemia: Alternative Immunosuppressive Treatments and Eltrombopag. A report from the 2014 EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties

    ... resulted in any benefit. Furthermore, the use of anti- lymphocyte agents other than h-ATG (rabbit-ATG, cyclophosphamide , ... standard h-ATG + CsA, irrespective of a more pronounced lymphocyte depletion observed with these alternative compounds. Thus, at least ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... AA was reproduced in animals, including mouse lymphocyte infusion models, which are used to study further etiology ... and significantly decrease the loss of HSCs in mouse lymphocyte infusion model of AA. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. STAT3-mutations indicate the presence of subclinical T cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

    ... Large granular lymphocyte leukemia (LGL) is often associated with immune cytopenias and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia

    ... 2/6 PNH(neg) patients had a CR and 4/6 had a PR. Lymphocyte subset immunophenotyping revealed that T-regulatory cells ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study.

    ... Large granular lymphocyte (LGL) leukemia is characterized by clonal expansion of ...

    Research Article last updated 07/20/2018 - 5:14pm.