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  1. Myelofibrosis (MF)

    ... drugs such as thalidomide and the related drugs lenalidomide and pomalidomide, which in some patients may improve blood ...

    Topic section last updated 07/07/2016 - 3:16pm.

  2. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... demethylating agents (azacytidine or decitabine , lenalidomide , etc) ALLOWED. Cohort B: Patients who have received prior ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  3. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... , hematopoietic growth factors, Zarnestra, Lenalidomide , arsenic, Imatinib, and corticosteroids, suberoylanilide ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  4. MDS Drug Therapy

    ... and high-risk patients with all sub-types of MDS Lenalidomide (Revlimid®) for transfusion-dependent MDS patients with ... Lenalidomide (Revlimid®) Lenalidomide ...

    Topic section last updated 03/10/2016 - 11:26pm.

  5. More is better: Combination therapies for myelodysplastic syndromes

    ... are currently three FDA-approved medications for MDS: lenalidomide , azacitidine , and decitabine .  Although these ... and acceptable side-effect profiles. -Azacitidine and lenalidomide, two FDA approved drugs in MDS, have also been combined with ...

    Research Review last updated 05/02/2016 - 9:14am.

  6. New therapeutics for myelodysplastic syndromes

    ... with myelodysplastic syndromes (MDS), including lenalidomide (Revlimidâ) and the azanucleosides, azacitidine ... Efforts are also underway to improve the effectiveness of lenalidomide, a drug with preferential activity in the group of MDS patients ...

    Research Review last updated 05/02/2016 - 9:28am.

  7. Recent developments in myelodysplastic syndromes

    ... – 2006 ( azacitidine , decitabine , and lenalidomide ), none of these are curative.  In addition, no new drugs have ... with chromosome 5q deletions are more likely to respond to lenalidomide. -High-resolution genome-wide techniques can detect ...

    Research Review last updated 05/02/2016 - 9:16am.

  8. Infections in myelodysplastic syndromes: a review

    ... drugs (5-azacytidine and decitabine ) and lenalidomide in recent years for treating MDS has affected the natural ... age and neutropenia did not increase risk. Lenalidomide therapy can be a double-edged sword. While profound neutropenia ...

    Research Review last updated 05/02/2016 - 9:28am.

  9. Alan List, MD

    ... (AML). His pioneering work led to the development of lenalidomide (Revlimid®) from the laboratory to clinical trials, which ...

    Leadership Award last updated 05/02/2016 - 12:18pm.

  10. Pathogenesis of MDS: An overview of molecular and non-molecular aspects of the disease

    ... are currently three FDA-approved medications for MDS: lenalidomide , azacitidine , and decitabine .  Although these ...

    Research Review last updated 05/02/2016 - 9:14am.