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  1. Treatments

    ... Iron Chelation Iron ...

    Topic section last updated 08/07/2018 - 2:28pm.

  2. Iron overload and chelation therapy in myelodysplastic syndromes

    ... Iron overload remains a concern in MDS patients especially those requiring ... unmask silent ones. Under these circumstances, iron chelation therapy could play an integral role in the management of these ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. When is iron overload deleterious, and when and how should iron chelation therapy be administered in myelodysplastic syndromes?

    ... Iron overload in MDS starts even before patients become red-blood cell ... which increase the level of oxidative stress. Iron chelation therapy (ICT) can rapidly lower NTBI and LPI and more slowly ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Toward resolving the unsettled role of iron chelation therapy in myelodysplastic syndromes

    ... syndromes (MDS) patients, eventually develop iron overload . Iron toxicity, via oxidative stress, can damage cellular ... organ function. In thalassemia major patients, iron chelation therapy lowered iron levels with recovery of cardiac and liver ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Iron chelation therapy in myelodysplastic syndromes.

    ... transfusion dependency can be long lasting, leading to iron overload . Iron chelation therapy may be a therapeutic option for these patients, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. The role of iron chelation therapy for patients with myelodysplastic syndromes.

    ... The appropriate role of iron chelation therapy in the management of patients with myelodysplastic ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Iron chelation therapy in myelodysplastic syndromes.

    ... To understand how to appropriately recognize and manage iron overload with iron chelation therapy (ICT) in patients with myelodysplastic syndromes ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Iron chelation therapy in myelodysplastic syndromes: where do we stand?

    ... Anemia leading to transfusion dependency (TD) and iron overload (IO) is commonly observed in patients with ... documentation of the beneficial effects of iron chelation therapy (ICT) on organ function and survival in MDS patients with ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

    ... of packed red blood cells leading to a secondary iron overload which might result in organ damage. Therefore, sufficient iron chelation therapy in selected patients is mandatory. Deferasirox ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Adequate iron chelation therapy for at least six months improves survival in transfusion-dependent patients with lower risk myelodysplastic syndromes

    ... syndromes (MDS) require transfusions at the risk of iron overload and associated organ damage, and death. Emerging evidence indicates that iron chelation therapy (ICT) could reduce mortality and improve survival in ...

    Research Article last updated 07/20/2018 - 5:15pm.