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  1. Recent Developments in Drug Therapy for Aplastic Anemia

    ... OBJECTIVE: This article reviews recent developments in immunosuppressive therapy (IST) for aplastic anemia (AA) patients who are not candidates ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Eltrombopag in aplastic anemia

    ... The treatment of aplastic anemia is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and ... refractory to IST. There is evidence that this drug works by directly stimulating marrow stem and progenitor cells thereby ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Eltrombopag restores tri-lineage hematopoiesis in refractory severe aplastic anemia which can be sustained on discontinuation of drug

    ... aplastic anemia (SAA) remain pancytopenic despite immunosuppressive therapy. We have previously demonstrated that eltrombopag ... patients with robust near-normalization of blood counts had drug discontinued at a median of 28.5 months after entry (range 9 to 37), and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromes.

    ... of the disease. Three drugs are now specifically Food and Drug Administration-approved for treatment of MDS: (1) azacitidine , ... results with each of these agents, plus results with immunosuppressive therapy, are reviewed to guide clinical decision making. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... Journal Title:  Curr Drug Targets Primary Author:  ... marrow. Historically the two treatments option have been immunosuppressive therapy (IST) and bone marrow transplantation (HSCT) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Immunosuppressive Therapy

    ... older patients with acquired aplastic anemia , immunosuppressive drug therapy is the treatment of choice. It is also used for aplastic ...

    Topic section last updated 07/06/2018 - 11:17am.

  7. My Son, the Athlete and Survivor

    ... match, but none of us were a match. Sam then received immunosuppressive therapy and he responded quickly and quite well to cyclosporine . But once he was weaned off that drug, his platelets began a slow descent to the point where, about a year ...

    Patient Chronicle last updated 04/26/2018 - 10:04am.

  8. Treatments

    ... care  to help you manage the symptoms of your MDS Drug Therapy with medicines specifically approved to treat MDS and stop abnormal cells from growing Immunosuppressive therapy, which can lower your body's immune response ...

    Topic section last updated 08/07/2018 - 2:28pm.

  9. Simona Pagliuca, MD

    ... allogeneic hematopoietic stem cell transplantation and immunosuppressive therapy based on two drugs: " cyclosporine " and ... results of standard therapy, by association with an other drug, called " eltrombopag ". Researchers want to answer a simple ...

    Grant Recipient last updated 08/15/2018 - 12:22pm.

  10. Long-term issues after Immunosuppressive therapy for Aplastic Anemia

    ... Journal Title:  Curr Drug Targets Primary Author:  ...

    Research Article last updated 06/23/2016 - 8:48am.