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  1. Immunological derangement in hypocellular myelodysplastic syndromes

    ... Hypocellular or hypoplastic myelodysplastic syndromes (HMDS) are a ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.

    ... stem cells . We analyzed patients with AA (N=93) and hypocellular MDS (hMDS, N=24) using single nucleotide polymorphism (SNP) ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Bone marrow hypocellularity does not affect tolerance or efficacy of azacitidine in patients with higher-risk myelodysplastic syndromes

    ... azacitidine in higher-risk myelodysplasia with hypocellular bone marrow (BM) are unknown. This post hoc AZA-001 ... Baseline BM biopsies of <30% cellularity were considered hypocellular with data evaluable from 299 patients (azacitidine n = 154, CCR ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Pediatric aplastic anemia and refractory cytopenia: A retrospective analysis assessing outcomes and histomorphologic predictors

    ... from inherited bone marrow failure syndrome and hypocellular refractory cytopenia of childhood (RCC). Historically, patients with hypocellular RCC have been given the diagnosis of AA. To assess the clinical ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia

    ... by severe defects in stem cell number resulting in hypocellular marrow and peripheral blood cytopenias. Minor paroxysmal ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia

    ... (BM) from patients with GATA2 deficiency is typically hypocellular with varying degrees of dysplasia. Distinguishing GATA2 ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Translocation (8;21) acute myeloid leukemia presenting as severe aplastic anemia

    ... was therefore insufficient to make the diagnosis of hypocellular acute myeloid leukemia. We discuss that further complementary ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Somatic mutations identify a sub-group of aplastic anemia patients that progress to myelodysplastic syndrome

    ... disorder. The distinction between acquired AA and hypocellular myelodysplastic syndrome (hMDS) is often difficult, ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Pediatric myelodysplastic syndromes: they do exist!

    ... pediatric MDS is more frequently associated with hypocellular bone marrow and monosomy 7 . Refractory ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Management of the refractory aplastic anemia patient: what are the options?

    ... with AA unresponsive to initial IST. Exclusion of hypocellular myelodysplastic syndrome and constitutional BM failure ...

    Research Article last updated 07/20/2018 - 5:15pm.