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  1. Paroxysmal nocturnal hemoglobinuria

    ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Loss of expression of neutrophil proteinase-3: a contributory factor in thrombotic risk in paroxysmal nocturnal hemoglobinuria.

    ... inositol-anchored proteins in paroxysmal nocturnal hemoglobinuria may be responsible for most of the clinical features of ... inositol-anchored proteins in paroxysmal nocturnal hemoglobinuria cells may influence expression of other membrane proteins. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Natural history of paroxysmal nocturnal hemoglobinuria clones in patients presenting as aplastic anemia.

    ... aplastic anemia paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

    ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Toward complement inhibition 2.0: Next generation anticomplement agents for paroxysmal nocturnal hemoglobinuria

    ... has revolutionized the treatment of paroxysmal nocturnal hemoglobinuria (PNH) with a major impact on its natural history. ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 04/11/2018 - 10:54am.

  6. Concurrent treatment of aplastic anemia/Paroxysmal Nocturnal Hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience

    ... aplastic anemia paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 04/11/2018 - 10:05am.

  7. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... clinically effective in hemolytic Paroxysmal Nocturnal Hemoglobinuria . However, the response is variable and some patients remain ... In 72 patients with hemolytic Paroxysmal Nocturnal Hemoglobinuria on eculizumab we tested the hypothesis that response may depend ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria.

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a debilitating and life-threatening disease in ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by complement-mediated intravascular ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria

    ... causes complement-mediated lysis in paroxysmal nocturnal hemoglobinuria (PNH), a disease that manifests after clonal expansion of ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:14pm.