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  1. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... BACKGROUND: Paroxysmal nocturnal hemoglobinuria is an acquired clonal disorder of the hemopoietic stem ... and hematologic results in 26 paroxysmal nocturnal hemoglobinuria patients who received hematopoietic stem cell ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Baseline characteristics and disease burden in patients in the international paroxysmal nocturnal hemoglobinuria registry

    ... Paroxysmal nocturnal hemoglobinuria is a rare, acquired disease associated with hemolytic ... data from patients with a confirmed paroxysmal nocturnal hemoglobinuria diagnosis or detectable paroxysmal nocturnal hemoglobinuria ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia

    ... peripheral blood cytopenias. Minor paroxysmal nocturnal hemoglobinuria populations and a short telomere length were ... to immunosuppressive therapy. The paroxysmal nocturnal hemoglobinuria populations and telomere length were detected by flow ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.

    ... cells are characteristic in paroxysmal nocturnal hemoglobinuria and are present in about 40-50% of patients with severe ... conducted a retrospective analysis of paroxysmal nocturnal hemoglobinuria clones measured by flow cytometry in 207 consecutive severe ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Paroxysmal nocturnal hemoglobinuria and pregnancy before the eculizumab era: the French experience

    ... Background Pregnancy in women with paroxysmal nocturnal hemoglobinuria is rare, with few reports on maternal and fetal mortality ... data on pregnancies in women with paroxysmal nocturnal hemoglobinuria was sent to all members of the French Society of Hematology in ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Successful pregnancy outcome in paroxysmal nocturnal hemoglobinuria (PNH) following escalated eculizumab dosing to control breakthrough hemolysis

    ... Pregnancy in women with paroxysmal nocturnal hemoglobinuria (PNH) is associated with increased maternal and fetal ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Paroxysmal Nocturnal Hemoglobinuria: A Complement-Mediated Hemolytic Anemia

    ... Paroxysmal nocturnal hemoglobinuria is manifests with a chronic hemolytic anemia from ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. The mutational landscape of paroxysmal nocturnal hemoglobinuria revealed: new insights into clonal dominance

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a disorder of hematopoietic stem cells ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations

    ... a potential treatment option for paroxysmal nocturnal hemoglobinuria , a rare hematological disorder characterized by ... aplastic anemia paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Improving cytopenia with splenic artery embolization in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab

    ... Paroxysmal nocturnal hemoglobinuria is a rare acquired stem cell disorder characterized by ... Diseases:  paroxysmal nocturnal hemoglobinuria (PNH) ...

    Research Article last updated 07/20/2018 - 5:15pm.