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  1. Clinical utility of lenalidomide in the treatment of myelodysplastic syndromes

    ... paradoxical BM hypercellularity, ineffective hematopoiesis , and increased risk of leukemic transformation. Risk ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. The complex pathophysiology of acquired aplastic anemia

    ... to immune mediated killing of HSPCs and/or ineffective hematopoiesis . Although the inciting autoantigens remain elusive, ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Clinical outcome after failure of hypomethylating therapy for myelodysplastic syndromes

    ... affect older patients, are characterized by ineffective hematopoiesis in one or more lineages of the bone marrow . In the ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Pathogenesis of myelodysplastic syndromes: an overview of molecular and non-molecular aspects of the disease

    ... stem cells generally characterized by inefficient hematopoiesis , dysplasia in one or more myeloid cell lineages, and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview

    ... The major clinical features of MDS are ineffective hematopoiesis , peripheral cytopenias, and an increased risk of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes

    ... stem cell disorders characterized by ineffective hematopoiesis and peripheral cytopenias. Chromosomal abnormalities and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Molecular pathogenesis of myelodysplastic syndromes

    ... hematologic disorders characterized by inefficient hematopoiesis , hypercellular bone marrow , dysplasia of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Total Lymphoid Irradiation-Antithymocyte Globulin Conditioning and Allogeneic Transplantation for Patients with Myelodysplastic Syndromes and Myeloproliferative Neoplasms

    ... globulin (ATG) permits the establishment of donor hematopoiesis necessary for the graft-versus-malignancy effect and is ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Bone marrow mesenchymal stem cells from aplastic anemia patients preserve functional and immune properties and do not contribute to the pathogenesis of the disease

    ... properties and their ability to support hematopoiesis , and they have been involved in the pathogenesis of several ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

    ... Hematopoiesis in health and disease results from complex interactions ...

    Research Article last updated 07/20/2018 - 5:15pm.