Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. High levels of vascular endothelial growth factor protein expression are associated with an increased risk of transfusion dependence in myelodysplastic syndromes

    ... the prognostic significance of vascular endothelial growth factor (VEGF) protein expression in 79 bone marrow biopsy specimens ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes.

    ... of the spliceosomal mutations on RNA splicing and cell growth have been evaluated only in a limited context to date, however, and the ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Cytokine signature profiles in acquired aplastic anemia and myelodysplastic syndromes.

    ... thrombopoietin and granulocyte colony-stimulating factor, with low levels of CD40 ligand, chemokine (C-X-C motif) ligand 5, ... ligand 5, chemokine (C-X-C motif) ligand 11, epidermal growth factor , vascular endothelial growth factor, and chemokine (C-C ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Revisiting use of growth factors in myelodysplastic syndromes

    ... with a high IPSS score. The advent of use of hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) and recombinant erythropoietin (EPO) has improved ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. The complex pathophysiology of acquired aplastic anemia

    ... including interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α) and tumor growth factor -beta (TGF-β), induce apoptosis of HSPCs, constituting a ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes

    ... that erlotinib has in vivo and in vitro off epidermal growth factor receptor (EGFR)-target activity in MDS. We conducted a phase II ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura

    ... chemokine (C-C motif) ligand 5 (CCL5), and epidermal growth factor (EGF) to be low in aplastic anemia (AA) patients and to be ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Myelodysplastic syndromes: therapy and outlook

    ... has been further enhanced with immunosuppressive agents, growth factor support, and biologic response modifiers. Initial treatment ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Azacitidine adverse effects in patients with myelodysplastic syndromes

    ... causes hematological toxicity that is managed with growth factor support, blood transfusions, and dose and schedule adjustment. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Immunological derangement in hypocellular myelodysplastic syndromes

    ... such as interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α). It has also been documented that some HMDS patients have ... cytokines such as TNF-α and transforming growth factor -β and to the inhibition of T-cell mediated immune responses ...

    Research Article last updated 07/20/2018 - 5:15pm.