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  1. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... related mortality and the rates of moderate and severe graft-versus-host disease (GvHD) at day 100. The investigators will describe event-free, and ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  2. Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

    ... Secondary To evaluate the incidence of acute graft-versus-host disease (GVHD) and chronic GVHD in patients treated with this regimen. ...

    Clinical Trial last updated 04/28/2016 - 8:53am.

  3. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD) . This is less likely when the recipient and donor have ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  4. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... 10 patients using sirolimus/Mycophenolate mofetil (MMF) graft-versus-host disease (GVHD) prophylaxis to gain further safety information and to ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  5. Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

    ... sometimes attack healthy tissues in a reaction called graft-versus-host disease (GVHD) , damaging organs such as the liver, intestines and skin. To ...

    Clinical Trial last updated 04/28/2016 - 11:28am.

  6. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... . Removing T-cells may help stop a side effect called Graft-Versus-Host Disease (GVHD) . Some studies have been done with CliniMACS, but the Food ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  7. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... tumor cells to NK cytotoxicity and protect against graft-versus-host disease (GVHD) , and (3) eliminating mycophenolate mofetil from the ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  8. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... mofetil is safe and effective in preventing severe graft-versus-host disease (GVHD) in most patients with hematologic malignancies undergoing ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  9. T-cell Depleted Alternative Donor Transplantation

    ... using the CliniMACS® device to prevent severe acute graft-versus-host disease (GVHD) in patients receiving a stem cell transplant from an ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  10. Phase II Study of 5-azacytidine Maintenance After Transplant for AML or MDS (UPCI 13-165)

    ... 5-aza has properties that suggest protection against graft-versus-host disease (GVHD) as well. Preliminary data shows that it is well tolerated ...

    Clinical Trial last updated 04/29/2016 - 10:26am.