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  1. TBI Dose De-escalation for Fanconi Anemia

    ... engraftment , whichever day is later, if no acute graft-versus-host disease (GVHD) . 4) If the subject is receiving bone marrow or ...

    Clinical Trial last updated 04/28/2016 - 9:06am.

  2. T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

    ... to participate in this study because treatment of their disease requires them to receive a stem cell transplant . Stem cells ... there is typically an increased risk of developing graft-versus-host disease (GVHD) , a high rate of transplant failure, and a ...

    Clinical Trial last updated 04/28/2016 - 12:15pm.

  3. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... cells in patients with leukemia, MDS, lymphoma, Hodgkin disease, or MM, after they have received an allogeneic stem cell transplant ... want to learn if giving AP1903 will help the symptoms of graft-versus-host disease (GvHD) that may occur after the T-cell infusion. ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.

  4. Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia

    ... Secondary To evaluate the incidence of acute graft-versus-host disease (GVHD) and chronic GVHD in patients treated with this regimen. ...

    Clinical Trial last updated 04/28/2016 - 8:53am.

  5. Allo HSCT Using RIC for Hematological Diseases

    ... The primary objective is to evaluate rates of acute graft-versus-host disease (GVHD) grades II-IV and chronic GVHD with an updated GVHD prophylaxis of ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  6. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD) . This is less likely when the recipient and donor have ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  7. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... selective T cell depletion works in preventing graft-versus-host disease (GVHD) in patients with acute lymphocytic leukemia, acute myeloid ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  8. Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

    ... sometimes attack healthy tissues in a reaction called graft-versus-host disease (GVHD) , damaging organs such as the liver, intestines and skin. To ...

    Clinical Trial last updated 04/28/2016 - 11:28am.

  9. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... 10 patients using sirolimus/Mycophenolate mofetil (MMF) graft-versus-host disease (GVHD) prophylaxis to gain further safety information and to ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  10. Clinical Trials Report for April 2016

    ... in the post transplant setting to prevent onset of acute graft-versus-host disease (GVHD) . The primary objective is to determine the incidence of ...

    Page last updated 08/10/2016 - 11:00am.