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  1. Long-term Survival and Late Effects among 1-year Survivors of Second Allogeneic Hematopoietic Cell Transplantation for Relapsed Acute Leukemia and Myelodysplastic Syndromes

    ... We analyzed the outcomes of patients who survived disease-free for 1-year or more following second allogeneic hematopoietic cell ... remission prior to second HCT, P<0.01). Chronic graft-versus-host disease (GVHD) developed in 43% and 75% of children and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. A randomized comparison of cyclophosphamide vs. reduced dose cyclophosphamide plus fludarabine for allogeneic hematopoietic cell transplantation in patients with aplastic anemia and hypoplastic myelodysplastic syndrome.

    ... failure (2.5 vs. 2.33 %; p = 0.959), acute graft-versus-host disease (GvHD) (15.0 vs. 23.3 %; p = 0.388), and chronic GvHD (16.7 vs. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Unmanipulated Haploidentical Hematopoietic Stem Cell Transplantation Achieved Outcomes Comparable With Matched Unrelated Donor Transplantation in Young Acquired Severe Aplastic Anemia

    ... cohorts had an increased cumulative incidence of acute graft-versus-host disease (GVHD) grades II to IV (43.9% ± 7.8% versus 12.5% ± 4.8%, ...

    Research Article last updated 06/13/2018 - 2:28pm.

  4. Comparison of Outcomes after Transplantation of G-CSF-Stimulated Bone Marrow Grafts versus Bone Marrow or Peripheral Blood Grafts from HLA-Matched Sibling Donors for Patients with Severe Aplastic Anemia.

    ... not different among the 3 treatment groups. Grade 2-4 acute graft-versus-host disease (aGVHD) (relative risk [RR] = 0.82, P = .539), grade 3-4 aGVHD (RR = ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Emerging Therapeutics for the Control of Chronic Graft-versus-Host Disease

    ... Chronic graft-versus-host disease (cGVHD) currently represents the leading cause of nonrelapse mortality ...

    Research Article last updated 01/04/2018 - 2:44pm.

  6. Repurposing older drugs to help prevent GVHD

    ... is safe and results in low incidence of acute graft-versus-host disease (GVHD) after reduced-intensity conditioning, related donor ...

    Article last updated 10/18/2017 - 8:48am.

  7. New positive results for GVHD treatment

    ... Link:  Ibrutinib Relieves Chronic Graft-Versus-Host Disease Symptoms Article ...

    Article last updated 01/12/2017 - 11:10am.

  8. FDA approves first drug to treat GVHD

    ... Ibrutinib Becomes First FDA-Approved Drug for Chronic Graft-Versus-Host Disease Article Source:  ...

    Article last updated 08/29/2017 - 7:55am.

  9. Ron Carlsen Beats Early Onset MDS; Grapples with Post-Transplant GVHD

    ... Ron Faces a New Health Challenge My chronic graft-versus-host disease (GVHD) started after the transplant, first in the most common ways; ...

    Patient Chronicle last updated 07/25/2018 - 10:28am.

  10. Drug reduces acute GVHD in unrelated HSCTs

    ... a potentially effective combination to mitigate graft-versus-host disease (GVHD) in the setting of matched unrelated donor myeloablative ...

    Article last updated 02/27/2017 - 1:45pm.