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  1. Haploidentical transplant in patients with myelodysplastic syndrome

    ... (HSCT), which usually results in a long-term, disease-free survival rate of between 30% and 50%, depending on the disease ... posttransplant cyclophosphamide (PT-CY) as graft-versus-host disease (GVHD) prophylaxis. The cumulative incidences of ...

    Research Article last updated 10/04/2017 - 9:19am.

  2. Discovered: Simple way to identify GVHD risks

    ... who received a bone marrow transplant will develop graft-versus-host disease, a common and often lethal complication, according to a study published ...

    Article last updated 02/09/2017 - 3:00pm.

  3. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... and mortality from graft failure and complications of graft-versus-host disease (GVHD) have limited enthusiasm for this approach. Here, we employed ...

    Research Article last updated 01/24/2017 - 10:04am.

  4. Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes

    ... respectively. The 100-day probability of Grade 2-4 acute graft-versus-host disease (GVHD) was 38%, and the 3-year probability of chronic GVHD was 28%. ...

    Research Article last updated 03/22/2017 - 9:24am.

  5. A Comparison of Outcomes for Cord Blood Transplant and Unrelated Bone Marrow Transplant in Adult Aplastic Anemia

    ... [CI], .32 to .94; P = .029), adjusted for age and graft-versus-host disease (GVHD) prophylaxis, which were other associated factors. Mortality ...

    Research Article last updated 08/15/2016 - 1:06pm.

  6. Strong results for SAA patients at Johns Hopkins

    ... 16 aplastic anemia patients free of disease after bone marrow transplant and chemo ... a year after their transplant, three developed mild graft-versus-host disease (GVHD) , a common complication of bone marrow ...

    Article last updated 02/07/2017 - 11:05am.

  7. Major news in BMT with half-match donors

    ... syndrome, also called pre-leukemia or MDS. By 2014, his disease had progressed to acute myeloid leukemia (AML), which affects ... the best choice,” Dr. Vusirikala said. “But the risk of graft-versus-host-disease (GvHD) following a transplant using a half-match is ...

    Article last updated 06/14/2016 - 3:02pm.

  8. Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

    ... had an increased cumulative incidence of grades II-IV acute graft-versus-host disease (aGVHD) (30.3 vs. 1.5%, P < 0.001), grades III-IV aGVHD (10.1 vs. ...

    Research Article last updated 02/03/2017 - 9:40am.

  9. Recent developments in bone marrow transplants

    ... prior to allogeneic HSCT significantly increased risk for graft-versus-host disease (GVHD)–related mortality in adults with T-cell leukemia/lymphoma. ...

    Article last updated 11/16/2016 - 2:56pm.

  10. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... two calcineurin inhibitor (CNI)-free strategies for Graft-versus-Host Disease (GVHD) prophylaxis to standard tacrolimus and methotrexate ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.