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  1. A randomized comparison of cyclophosphamide vs. reduced dose cyclophosphamide plus fludarabine for allogeneic hematopoietic cell transplantation in patients with aplastic anemia and hypoplastic myelodysplastic syndrome.

    ... comprising reduced cyclophosphamide (Cy), fludarabine , and anti-thymocyte globulin (ATG) (Cy-Flu-ATG) was used to ... Cy at 200 mg/kg. Those in the Cy-Flu-ATG arm received fludarabine (Flu) at 150 mg/m(2) and Cy at 100 mg/kg. A total of 83 patients ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Fludarabine, cyclophosphamide, antithymocyte globulin, with or without low dose total body irradiation, for alternative donor transplants, in acquired severe aplastic anemia: a retrospective study from the EBMT-SAA working party.

    ... regimen, patients received either a combination of fludarabine , cyclophosphamide , and antithymocyte globulin ... 5-year survival was 73% for the group that received fludarabine, cyclophosphamide, and antithymocyte globulin and 79% for the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... of reduced-dose cyclophosphamide (CY) and fludarabine (FDR) have been investigated for use in allogeneic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... cyclophosphamide (Cy, 25 mg/kg for four days), fludarabine (Flu, 30 mg/m2 for four days), and rabbit ATG (2.5 mg/kg for ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Alemtuzumab with fludarabine and cyclophosphamide reduces chronic graft versus host disease after allogeneic stem cell transplantation for acquired aplastic anemia.

    ... (MSD) (n=21) and unrelated donors, UD (n=29), using fludarabine 30mg/m(2) for 4 days, cyclophosphamide 300mg/m(2) for ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels

    ... of cyclophosphamide (CY) dose deescalation in a fludarabine -based conditioning regimen for bone marrow ... received fixed doses of antithymocyte globulin , fludarabine, and low-dose total body irradiation. The starting CY dose was 150 ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Engraftment of heavily transfused patients with severe aplastic anemia with a fludarabine-based regimen

    ... complications. In this study, we focused on evaluating a fludarabine -based conditioning regimen, among 83 patients with SAA. Patients were treated with fludarabine (40 mg/m(2) /d; day [-5 to -2]) and cyclophosphamide (50 mg/kg/d; ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Second allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia

    ... patients who were conditioned with regimens containing fludarabine and melphalan were alive with hematopoietic recovery. These ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... our center. The conditioning regimen consisted of BU, fludarabine , CY and anti-thymocyte globulin. All patients received ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Long-term outcome of fludarabine-based reduced intensity allogeneic hematopoietic cell transplantation for debilitating paroxysmal nocturnal hemoglobinuria

    ... transplant (HCT). All received cyclophosphamide / fludarabine +/- ATG followed by a G-CSF mobilized HCT from an HLA-matched ...

    Research Article last updated 07/20/2018 - 5:15pm.