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  1. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... (TJU) RIC 2 step approach. III. To evaluate engraftment rates and lymphoid reconstitution in patients treated on the ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  2. Telomere Length and Allogeneic Hematopoietic Cell Transplantation for Severe Aplastic Anemia

    ... between donor telomere length and bone marrow engraftment or incidence of graft-versus-host disease (GVHD) .   ... influence the HSCT outcome is still lacking. Bone marrow engraftment failure and GVHD incidence are major factors that impact HSCT ...

    Research Review last updated 05/02/2016 - 9:13am.

  3. Phase 1 Study of TCP-ATRA for Adult Patients With AML and MDS (TCP-ATRA)

    ... treatment with ATRA and TCP markedly diminished the engraftment of primary human AML cells in murine models, indicating that ...

    Clinical Trial last updated 04/29/2016 - 12:33pm.

  4. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... how often subjects had complications of GVHD and engraftment failure. People with aplastic anemia who have ...

    Clinical Trial last updated 04/21/2016 - 1:19pm.

  5. CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

    ... with malignant and non-malignant disease with successful engraftment and has shown some improvement in GVHD. We do not know if CD34+ ...

    Clinical Trial last updated 04/28/2016 - 8:36am.

  6. Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

    ... -based conditioning regimens provide stable engraftment and may avoid the toxicities seen after HCT for DC, but studies ...

    Clinical Trial last updated 04/27/2016 - 8:49am.

  7. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... regimen-related toxicity while maintaining better engraftment , this study is to evaluate the effectiveness and safety of ... survival probability at 3 months, 6 months and 1 year. Engraftment at 3 months, 6 months and 1 year Incidence of graft versus host ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  8. Safety Study of Cord Blood Units for Stem Cell Transplants

    ... rejection Assess incidence of neutrophil engraftment > 500 /ul Determine 1 year survival after cord blood ... incidence of chronic GVHD Determine platelet engraftment of > 20,000/ul and > 50,000/ul Determine CBU-derived ...

    Clinical Trial last updated 04/27/2016 - 2:25pm.

  9. New York Blood Center National Cord Blood Program

    ... endpoints, primarily myeloid and platelet engraftment , transplant related mortality, overall survival, acute and ...

    Clinical Trial last updated 04/27/2016 - 3:36pm.

  10. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... then if there is no evidence of active GVHD and donor engraftment is > 95% (or by Principal Investigator [PI] approval) taper ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.