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  1. Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)

    ... research study is to compare how 2 different drugs, decitabine and azacitidine , when given on a shorter than standard ... Azacitidine Decitabine Phase:  ...

    Clinical Trial last updated 04/28/2016 - 10:22am.

  2. Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

    ... hydrochloride and cytarabine when followed by decitabine or observation in treating older patients with newly diagnosed ... as clofarabine, daunorubicin hydrochloride, cytarabine, and decitabine, work in different ways to stop the growth of cancer cells, either ...

    Clinical Trial last updated 04/28/2016 - 12:10pm.

  3. Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

    ... leukemia or myelodysplastic syndromes respond to decitabine . This study will contribute to the efforts to find effective and ... Associated Drug(s):  Decitabine Phase:  ...

    Clinical Trial last updated 04/29/2016 - 12:30pm.

  4. Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

    ... study is to learn if the combination of vosaroxin and decitabine can help to control AML or MDS. The safety of these drugs will ... Associated Drug(s):  Decitabine Phase:  ...

    Clinical Trial last updated 04/29/2016 - 11:49am.

  5. Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm

    ... This clinical trial studies decitabine and cytarabine in treating older patients with newly diagnosed ... neoplasm. Drugs used in chemotherapy , such as decitabine and cytarabine, work in different ways to stop the growth of cancer ...

    Clinical Trial last updated 04/21/2016 - 1:23pm.

  6. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... treatment with demethylating agents (azacytidine or decitabine , lenalidomide , etc) ALLOWED. Cohort B: Patients who ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  7. Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral CDAi in Patients With MDS

    ... Associated Drug(s):  Decitabine Phase:  ... Escalation Oral investigational product and approved IV decitabine Other Names: E7727 oral decitabine IV decitabine Drug: ASTX727 ...

    Clinical Trial last updated 04/27/2016 - 2:05pm.

  8. Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia

    ... stem cell transplant Prior azacitidine , decitabine , or midostaurin Patients with known impairment of ...

    Clinical Trial last updated 06/03/2016 - 2:24pm.

  9. New therapeutics for myelodysplastic syndromes

    ... the azanucleosides, azacitidine (Vidazaâ) and decitabine (Dacogenâ).  Although these agents represent a significant ... the MDS clone:   The azanucleosides (azacitidine and decitabine) remain the best treatment option for many higher-risk MDS ...

    Research Review last updated 05/02/2016 - 9:28am.

  10. More is better: Combination therapies for myelodysplastic syndromes

    ... for MDS: lenalidomide , azacitidine , and decitabine .  Although these agents can be effective in the treatment of ... an epigenetic approach, where one combines azacitidine or decitabine (the class of drugs known as hypomethylating agents) with a class of ...

    Research Review last updated 05/02/2016 - 9:14am.