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  1. SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution

    ... counts, lower lactate dehydrogenase levels, good-risk cytogenetics and mutations of DNMT3A, but inversely related to ASXL1 ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher-risk myelodysplastic syndromes.

    ... with azacitidine. Each patient, one with normal cytogenetics at relapse; one with a 18 abnormality; and one with ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia

    ... CD4:CD8 ratios. Atypical megakaryocytes and abnormal cytogenetics were more common in GATA2 marrows. CD34+ cells were ... routine BM flow cytometry , morphology and cytogenetics, in patients who present with cytopenia (s), can identify ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update

    ... (AML) arising from MDS, and in MDS with poor-risk cytogenetics . Furthermore, decitabine has been studied in the allograft ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Revised International Prognostic Scoring System (IPSS) Predicts Survival and Leukemic Evolution of Myelodysplastic Syndromes Significantly Better Than IPSS and WHO Prognostic Scoring System: Validation by the Gruppo Romano Mielodisplasie Italian Regional

    ... and bone marrow counts, informative cytogenetics , and follow-up data.ResultsWe validated the IPSS-R score as a ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Perceptions of Disease State, Treatment Outcomes, and Prognosis Among Patients with Myelodysplastic Syndromes: Results From an Internet-Based Survey.

    ... of their blast percentage, and 28% were unaware of their cytogenetics . Patients were unlikely to recall having their MDS described ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

    ... Performance status ≥ 2, intermediate- and poor-risk cytogenetics , presence of circulating blasts, and red blood cell ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Transplantation for myelodysplastic syndromes 2013.

    ... relapse-free survival even in patients with high-risk cytogenetics . The optimal stem cell source may differ for different patient ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: A report on 62 cases.

    ... showed that could be readily identified as MDS prior to cytogenetics . Fourteen percent of patients with isolated del 20q ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Clinical effect of point mutations in myelodysplastic syndromes

    ... mutation, including 52% of the patients with normal cytogenetics . Mutations in RUNX1, TP53, and NRAS were most strongly ...

    Research Article last updated 07/20/2018 - 5:14pm.