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  1. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution.

    ... 22 patients received cyclophosphamide at 120 mg/kg plus cyclosporine , antibacterial, antiviral, and antifungal prophylaxis. ...

    Research Article last updated 10/07/2014 - 8:33am.

  2. Moderate, Severe, and Very Severe Aplastic Anemia: How are treatment decisions made?

    ... involve some sort of immunosuppression, as basic as cyclosporine alone, but also eltrombopag is being tested at the NIH ...

    Interview last updated 10/14/2015 - 12:47pm.

  3. Platelet drug shows clinical benefits for severe, unresponsive aplastic anemia

    ... and a trial for combining eltrombopag with ATG and cyclosporine in children and adults with previously-untreated aplastic ...

    Interview last updated 07/06/2012 - 3:42pm.

  4. Immunosuppressive Therapy

    ... include ATG ( antithymocyte globulin ) and cyclosporine . This therapy helps some MDS patients, especially those ... few weeks afterward to prevent or treat serum sickness. Cyclosporine How Cyclosporine Works Cyclosporine prevents ...

    Page last updated 01/20/2015 - 4:45pm.

  5. Immunosuppression and Stem Cell Transplantation – How Are These Treatments Chosen?

    ... is used, most often anti-thymocyte globulin (ATG), cyclosporine , or tacrolimus, and sometimes high dose cyclophosphamide ...

    Interview last updated 07/15/2015 - 10:19am.

  6. Overlap Syndromes: When PNH Appears with Aplastic Anemia or MDS

    ... immunosuppression, generally being horse ATG followed by cyclosporine . But patients with PNH/aplastic anemia overlap maybe not ... kidney function. Patients with aplastic anemia who require cyclosporine can experience an effect of the drug on their kidneys, and rare ...

    Interview last updated 05/14/2015 - 1:53pm.

  7. 2013 Scholarships Awarded to Special Group of Young People

    ... started receiving two rounds of ATG treatment as well as cyclosporine drug therapy. Haley went through more than 75 blood ... and weeks made my family and me more hopeful. After years of cyclosporine and many needle pokes later, I have been deemed to be recovered by ...

    Page last updated 06/24/2015 - 10:22am.

  8. Overlap Syndromes: When PNH Appears with Aplastic Anemia

    ... immunosuppression, generally being horse ATG followed by cyclosporine . But patients with PNH-aplastic anemia overlap maybe not ... kidney function. Patients with aplastic anemia who require cyclosporine can experience an effect of the drug on their kidneys, and rare ...

    Interview last updated 04/15/2015 - 9:39am.

  9. MDS Drug Information

    ... V idaza cyclosporine N eoral, S ...

    Page last updated 01/20/2015 - 4:46pm.

  10. Clinical Trials Report for February 2015

    ... (hATG), given in combination with methylprednisolone, cyclosporine , and G-CSF ( filgrastim or pegfilgrastim), can help to ... cells may help treat the disease. Methylprednisolone and cyclosporine work to suppress immune cells called lymphocytes. This may help to ...

    Page last updated 01/29/2015 - 10:10am.