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  1. Antibodies in the treatment of aplastic anemia.

    ... (ATG) is considered pivotal and the addition of cyclosporine improves the overall response rate. This antibody is ... remain unsolved in relation to the combination of ATG and cyclosporine: cost, toxicity and late clonal disorders. In recent years, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia

    ... Anti-thymocyte globulin (ATG) plus cyclosporine is effective in restoring hematopoiesis in severe ... disease, patients were randomized between rabbit ATG plus cyclosporine (n=27) vs. alemtuzumab (n=27); the response rate for alemtuzumab ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Survival After Immunosuppressive Therapy in Children with Aplastic Anemia

    ... using equine antithymocyte globulin (e-ATG) and cyclosporine (CsA). DESIGN: Prospective data entry as per a specified ... Immunosuppressive therapy using equine ATG and cyclosporine. MAIN OUTCOME MEASURES: Overall response and overall ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia

    ... A combination of horse anti-thymocyte globulin and cyclosporine produces responses in 60-70% of patients with severe ... a phase II study of rabbit anti-thymocyte globulin and cyclosporine as first-line therapy for severe aplastic anemia. DESIGN AND ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation.

    ... treated with antithymocyte globulin (ATG) and cyclosporine (CSA). Between January 2002 and July 2008, 192 patients with ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.

    ... therapy with a horse anti-thymocyte globulin plus cyclosporine regimen from 2000 to 2008. RESULTS: The presence of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Aplastic anemia: first-line treatment by immunosuppression and sibling marrow transplantation.

    ... the combination of antithymocyte globulin and cyclosporine A for patients without a sibling donor and HLA ... cell source, and graft-versus-host diease prophylaxis using cyclosporine A and methotrexate. It is against these standard treatment ...

    Research Article last updated 07/20/2018 - 5:14pm.

  8. Rabbit antithymocyte globulin versus horse antithymocyte globulin for treatment of acquired aplastic anemia: a retrospective analysis

    ... centers. Patients were treated with rATG or hATG plus cyclosporine A. Over half were classified, as having severe AA (SAA) or ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Aplastic Anemia: Alternative Immunosuppressive Treatments and Eltrombopag. A report from the 2014 EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties

    ... is horse anti-thymocyte globuline (h-ATG) combined with cyclosporine A (CsA), which results in a long term survival around 65-70%. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Eltrombopag in aplastic anemia

    ... therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine , to which two thirds of patients respond. However, a ...

    Research Article last updated 07/20/2018 - 5:15pm.