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  1. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... therapy. HLA-haploidentical BMT using posttransplant cyclophosphamide conditioning regimens is now a reasonable second-line ...

    Research Article last updated 11/01/2016 - 1:55pm.

  2. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... therapy. HLA-haploidentical BMT using posttransplant cyclophosphamide conditioning regimens is now a reasonable second-line ...

    Research Article last updated 10/06/2016 - 9:48am.

  3. Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

    ... siblings following a standard conditioning regimen with cyclophosphamide (50 mg/kg/day × 4 days) and horse antithymocyte ...

    Research Article last updated 09/13/2016 - 12:50pm.

  4. Taming the nausea, vomiting caused by chemo

    ... and vomiting, including cisplatin, doxorubicin, and cyclophosphamide . The antiemetic drugs—all of which act on components ... all of whom were being treated with cisplatin or with cyclophosphamide and doxorubicin, were randomly assigned to receive olanzapine ...

    Article last updated 08/11/2016 - 3:27pm.

  5. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... intravenously (IV) over 1 hour on days -6 to -2; cyclophosphamide IV over 1 hour on days -6 and -5; and undergo total body ... 0. POST-TRANSPLANT IMMUNOSUPPRESSION: Patients receive cyclophosphamide IV over 1 hour on days 3 and 4, and mycophenolate mofetil ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  6. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... Antithymocyte Globulin Cyclophosphamide Filgrastim Fludarabine ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  7. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... of transplants, there is a need to use high doses of cyclophosphamide to kill GVHD-causing haplo T-cells which can make patients ... for a few days after the transplant. Further, treatment with cyclophosphamide after the transplant can also delay the time to engraftment ...

    Interview last updated 10/04/2017 - 1:36pm.

  8. Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis

    ... main purpose of this study is to assess the effects of cyclophosphamide (cytoxan) in the post transplant setting to prevent onset ... Hematopoeitic Cell Transplant (HCT) using post-transplant cyclophosphamide (cytoxan) for patients with human leukocyte antigen ( ...

    Clinical Trial last updated 04/27/2016 - 9:38am.

  9. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

    ... PubMed Abstract:  "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does ... at long-term. One attempt to improve IST results is cyclophosphamide . It was first used in high dose (200 mg/kg) as an ...

    Research Review last updated 05/02/2016 - 9:13am.

  10. Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Sy

    ... when given together with fludarabine phosphate, cyclophosphamide , total-body irradiation, and donor bone marrow ... chemotherapy drugs, such as fludarabine phosphate and cyclophosphamide, and total-body irradiation before a donor bone marrow ...

    Clinical Trial last updated 04/28/2016 - 1:01pm.