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  1. A randomized comparison of cyclophosphamide vs. reduced dose cyclophosphamide plus fludarabine for allogeneic hematopoietic cell transplantation in patients with aplastic anemia and hypoplastic myelodysplastic syndrome.

    ... Recently, a less toxic regimen comprising reduced cyclophosphamide (Cy), fludarabine , and anti-thymocyte globulin ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution

    ... line therapy of aplastic anemia with high dose cyclophosphamide causes toxicity and increased short-term mortality. We investigated cyclophosphamide at a lower "moderate" dose, in combination with aggressive ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... BACKGROUND: Cyclophosphamide -based conditioning regimens and allogeneic hematopoietic ... with high (200 mg/kg) and low (60 mg/kg) dose cyclophosphamide as upfront treatment in newly diagnosed pediatric patients ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. High-dose cyclophosphamide for severe aplastic anemia: long-term follow-up.

    ... immunosuppressive therapy, and high-dose cyclophosphamide . Here, we report long-term follow-up on 67 SAA patients ... and 23 refractory ) treated with high-dose cyclophosphamide. At 10 years, the overall actuarial survival was 88%, the ... with refractory SAA fared less well after high-dose cyclophosphamide therapy; at 10 years, overall actuarial survival, response, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Long-term follow-up after allogeneic stem cell transplantation in patients with severe aplastic anemia after cyclophosphamide plus antithymocyte globulin conditioning

    ... we decided some years ago to use the combination of cyclophosphamide and antithymocyte globulin . We report the ... transplanted from June 1991 to February 2010, following cyclophosphamide (200mg/kg) and antithymocyte globulin (2.5 mg/kg/day x 5 ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Fludarabine, cyclophosphamide, antithymocyte globulin, with or without low dose total body irradiation, for alternative donor transplants, in acquired severe aplastic anemia: a retrospective study from the EBMT-SAA working party.

    ... received either a combination of fludarabine , cyclophosphamide , and antithymocyte globulin (n=52, median age 13 ... survival was 73% for the group that received fludarabine, cyclophosphamide, and antithymocyte globulin and 79% for the group given the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... Conditioning regimens consisting of reduced-dose cyclophosphamide (CY) and fludarabine (FDR) have been investigated ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... results of a novel conditioning regimen of reduced dose cyclophosphamide (Cy, 25 mg/kg for four days), fludarabine (Flu, 30 ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. High-Dose Cyclophosphamide in Comparison with Antithymocyte Globulin for Treatment of Acquired Severe Aplastic Anemia

    ... A modified high-dose cyclophosphamide (HD-CTX) plus cyclosporine (CsA) regimen was ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Different outcomes between cyclophosphamide plus horse or rabbit antithymocyte globulin for HLA-identical sibling bone marrow transplantation in severe aplastic anemia

    ... (BMT) in severe aplastic anemia (SAA) is cyclophosphamide (CY) and horse antithymocyte globulin (ATG). Horse ...

    Research Article last updated 07/20/2018 - 5:14pm.