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  1. Outcome of patients treated for myelodysplastic syndromes without deletion 5q after failure of lenalidomide therapy

    ... remains relatively prolonged, though with a wide range. Clinical trial participation remains the recommendation for these patients even if ...

    Research Article last updated 02/21/2017 - 9:43am.

  2. Strong results for SAA patients at Johns Hopkins

    ... and an author of the report. Results of the small clinical trial have already prompted the organization of a larger national trial ...

    Article last updated 02/07/2017 - 11:05am.

  3. Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher risk myelodysplastic syndromes

    ... A phase 2 randomized, placebo -controlled clinical trial of azacitidine and pracinostat was conducted in patients who had ...

    Research Article last updated 02/03/2017 - 11:12am.

  4. Medical “Must-See” TV in May

    ... and followed first in human patients throughout their entire trial. This unique access is the product of Hoffman’s nearly twenty years of ... an elemental level and at our most profound.” "The NIH Clinical Center’s more than 60-year history has resulted in remarkable ...

    Article last updated 02/02/2017 - 9:48am.

  5. PACCT+ Patient Committee Holds First Meeting

    ... On September 24, the AAMDSIF Patient Advisory Council on Clinical Trials (PACCT+) members met in Arlington, Virginia for an orientation ... members, and learn from two experts about clinical trial design and the state of current bone marrow failure (BMF) ...

    Article last updated 01/23/2017 - 2:12pm.

  6. TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes

    ... Background The molecular determinants of clinical responses to decitabine therapy in patients with acute myeloid ... 84 adult patients with AML or MDS in a single-institution trial of decitabine to identify somatic mutations and their relationships to ...

    Research Article last updated 01/26/2017 - 10:07am.

  7. MEDALIST Trial

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements. This is a Phase ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  8. A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of AG-120 in advanced hematologic malignancies that harbor an ...

    Clinical Trial last updated 02/22/2017 - 11:21am.

  9. The National Myelodysplastic Syndromes Natural History Study

    For more details on this clinical trial, including contact information, please see this trial’s listing on ... (ICUS).  Participants will be followed long term.  Clinical data, blood, and tissue samples will be collected to establish a ...

    Clinical Trial last updated 02/23/2017 - 1:36pm.

  10. New positive results for GVHD treatment

    ... of stem cell transplant , findings from a small clinical trial show. Patients in the trial had blood cancers and were ...

    Article last updated 01/12/2017 - 11:10am.