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  1. Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System.

    ... care without specific therapy, with AML-like chemotherapy , or with other therapy regimens (low-dose chemotherapy, demethylating agents, immune modulating agents, valproic acid, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Treatment of Higher-Risk Myelodysplastic Syndromes After Failure of Hypomethylating Agents

    ... use of HMAs, add-back strategies, other palliative chemotherapy options, and provide an overview for several promising ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. More is better: Combination therapies for myelodysplastic syndromes

    ... histone deacetylase inhibitors, growth factors, and chemotherapy among others. In this paper we review the current literature ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Transplants in Myelodysplastic Syndromes

    ... of de novo but also of secondary forms after prior chemotherapy or radiotherapy, respectively, is anticipated within the next ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Lack of objective response of myelodysplastic syndromes and acute myeloid leukemia to decitabine after failure of azacitidine

    ... leukemia (AML) unlikely to benefit from cytotoxic chemotherapy . Switching hypomethylating agents after treatment failure is ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview

    ... syndromes such as Fanconi anemia and receipt of chemotherapy and radiation treatment. In recent years a significant ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Update on the pharmacotherapy for myelodysplastic syndromes

    ... relied upon supportive care and intensive chemotherapy . The last decade has seen many scientific and therapeutic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Myelodysplastic syndromes

    ... in a third of patients. 15% of cases occur after chemotherapy or radiotherapy for a previous cancer; the syndromes are most ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Prognosis of acute myeloid leukemia transformed from myelodysplastic syndromes: A multicenter retrospective study

    ... received disease-modifying therapies (DMT) that included chemotherapy (CHT) for 65 patients, allogeneic stem-cell transplantation ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Recent advances in the management of therapy-related myelodysplastic syndromes and acute myeloid leukemia.

    ... studies have identified poor-risk cytogenetics , chemotherapy resistance, comorbidities from prior cancer and therapy, and ...

    Research Article last updated 07/20/2018 - 5:15pm.