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  1. Bone marrow hypocellularity does not affect tolerance or efficacy of azacitidine in patients with higher-risk myelodysplastic syndromes

    ... hoc AZA-001 trial analysis assessed whether baseline BM cellularity affected the overall survival (OS) advantage demonstrated with ... care regimens (CCR). Baseline BM biopsies of <30% cellularity were considered hypocellular with data evaluable from 299 patients ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

    ... were cytoreduced according to pre-defined criteria ( cellularity <20% and blasts <10%). Marrow cellularity (P<0.0001) and blast% (P=0.03) were reduced. Toxicities were ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. STAT3-mutations indicate the presence of subclinical T cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

    ... a STAT3 mutant clone showed lower degree of BM cellularity and a higher frequency of developing chromosome 7 ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Unveiling the paradoxical nature of myelodysplastic syndromes (MDS): Why hypercellular marrow strongly favors accelerated apoptosis.

    ... peripheral blood cytopenias and increased bone marrow cellularity . This apparent paradox has been interpreted as a sign of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. High levels of vascular endothelial growth factor protein expression are associated with an increased risk of transfusion dependence in myelodysplastic syndromes

    ... (MDS). VEGF levels normalized for bone marrow cellularity (VEGF index [VEGFi]) were higher in the World Health ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes.

    ... Histological examination revealed a comparable BM cellularity and BM blast percentage, but markedly increased megakaryocytes ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. My Son, the Athlete and Survivor

    ... they ran more tests and did more marrow biopsies. The cellularity was spotty at 10-40% but nothing else in the bloodwork stood ...

    Patient Chronicle last updated 04/26/2018 - 10:04am.

  8. New study on SCT therapy for SAA, MDS patients

    ... and hypoplastic MDS is characterized by decreased marrow cellularity . Cordin is a variety of stem cell transplantation that uses ...

    Article last updated 08/22/2017 - 9:41am.

  9. Clinical Outcomes in Adult Patients with Aplastic Anemia- a single institution experience

    ... with/without G-CSF or eltrombopag ). While marrow cellularity did not correlate with peripheral-blood counts at 3 months, ...

    Research Article last updated 09/13/2017 - 7:40am.

  10. Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS)

    ... Although most MDS patients have normal or increased BM cellularity (NH-MDS), some have hypocellular BM (h-MDS). The ...

    Research Article last updated 09/19/2016 - 11:07am.