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  1. Successful bone marrow transplantation for children with aplastic anemia based on a best-available evidence strategy.

    ... acceptable. Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... in a fludarabine -based conditioning regimen for bone marrow transplantation from unrelated donors in patients with severe ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP)

    ... characterized by pancytopenia and hypoplastic bone marrow . The incidence is 2-3/million inhabitants/year, in Europe, but ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Pediatric myelodysplastic syndromes: they do exist!

    ... cytopenia (s) and normal or hypercellular bone marrow with dysplasia in ≥1 blood cell lineages. MDS frequently evolves ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Pediatric aplastic anemia and refractory cytopenia: A retrospective analysis assessing outcomes and histomorphologic predictors

    ... Pediatric acquired aplastic anemia (AA) is a bone marrow disorder that is difficult to distinguish from inherited bone ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Somatic mutations identify a sub-group of aplastic anemia patients that progress to myelodysplastic syndrome

    ... is based solely on morphological changes in blood and bone marrow . We postulated that somatic mutations are present in a subset of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Outcome of Pediatric Acquired Aplastic Anemia: A Developing World Experience.

    ... history, physical examination, complete blood count, bone marrow aspirate, and biopsy were retrieved for all children <18 years, with ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Myelodysplastic syndromes: What do hospitalists need to know?

    ... in any patient with unexplained cytopenias, and a bone marrow evaluation is ultimately needed to make the diagnosis and exclude ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Reduced ribosomal RNA expression and increased ribosomal DNA promoter methylation in CD34+ cells of patients with myelodysplastic syndromes

    ... increases in DNA methylation have been documented in bone marrow cells from MDS patients, the methylation signatures of specific gene ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. The complex pathophysiology of acquired aplastic anemia

    ... that intrinsic and/or secondary deficits in HSPCs and bone marrow mesenchymal stem cells may underlie the development of bone ...

    Research Article last updated 07/20/2018 - 5:15pm.