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  1. Somatic mutations identify a sub-group of aplastic anemia patients that progress to myelodysplastic syndrome

    ... is based solely on morphological changes in blood and bone marrow . We postulated that somatic mutations are present in a subset of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Outcome of Pediatric Acquired Aplastic Anemia: A Developing World Experience.

    ... history, physical examination, complete blood count, bone marrow aspirate, and biopsy were retrieved for all children <18 years, with ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Myelodysplastic syndromes: What do hospitalists need to know?

    ... in any patient with unexplained cytopenias, and a bone marrow evaluation is ultimately needed to make the diagnosis and exclude ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Reduced ribosomal RNA expression and increased ribosomal DNA promoter methylation in CD34+ cells of patients with myelodysplastic syndromes

    ... increases in DNA methylation have been documented in bone marrow cells from MDS patients, the methylation signatures of specific gene ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. The complex pathophysiology of acquired aplastic anemia

    ... that intrinsic and/or secondary deficits in HSPCs and bone marrow mesenchymal stem cells may underlie the development of bone ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Professionals

    ... A Brave New World: The Clinical Management of Bone Marrow Failure and Myeloid Malignancy in a Time of Personalized Therapy ...

    Page last updated 08/15/2018 - 1:04pm.

  7. Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

    ... was 35 weeks. Of 30 evaluable patients with follow-up bone marrow biopsies, 12 (40%) achieved complete (n = 5) or partial ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Orlando (FL) Community Connection Support Group Meeting

    » Community Event: Saturday, August 4, 2018 - 12:30pm to 3:00pm

    ... the Roseada Room on the 2nd Floor. At this meeting, bone marrow failure disease patients and families will connect with each other, ...

    Community Event last updated 07/23/2018 - 9:03am.

  9. Atlanta (GA) Community Connection Support Group Meeting

    » Community Event: Saturday, August 4, 2018 - 1:00pm to 3:00pm

    ... on Saturday, August 4, 2018 at 1:00PM. At this meeting, bone marrow failure disease patients and families will connect with each other, ...

    Community Event last updated 07/23/2018 - 8:45am.

  10. Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations

    ... Aplastic anemia (AA) is a bone marrow failure syndrome characterized by pancytopenia and an empty ...

    Research Article last updated 07/20/2018 - 5:15pm.