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  1. Improved risk stratification by the integration of the revised International Prognostic Scoring System with the Myelodysplastic Syndromes Comorbidity Index

    ... Myelodysplastic syndromes (MDS) comprise bone marrow failure diseases with a diverse clinical outcome. For improved risk ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Complement Blockade with a C1 Esterase Inhibitor in Paroxysmal Nocturnal Hemoglobinuria

    ... with a complement-mediated hemolytic anemia , bone marrow failure and a propensity for thrombosis . These patients ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Clinical and genetic predictors of prognosis in myelodysplastic syndromes

    ... of peripheral blood cytopenias, the proportion of bone marrow blasts , and specific karyotype abnormalities. Other factors ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Molecular pathogenesis of myelodysplastic syndromes

    ... inefficient hematopoiesis , hypercellular bone marrow , dysplasia of blood cells and cytopenias. Most patients are ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Myelodysplastic syndromes in the United States: an update for clinicians

    ... syndromes (MDS) are heterogeneous malignant bone marrow disorders diagnosed most often in elderly white persons. MDS have ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Biosimilar epoetin in elderly patients with low-risk myelodysplastic syndromes improves anemia, quality of life, and brain function

    ... of clonal hematopoietic disorders characterized by bone marrow failure and a risk of progression to acute myeloid leukemia (AML). ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Effectiveness and safety of different azacitidine dosage regimens in patients with myelodysplastic syndromes or acute myeloid leukemia

    ... syndromes , or acute myeloid leukemia with 20-30% bone marrow blasts . Patients were treated with azacitidine, with one of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum

    ... and the extrinsic influences of other cells in the bone marrow (BM) niche. Advances in stem cell biology, molecular genetics, and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... areas of general consensus, including the need for a bone marrow evaluation, cytogenetic and specific fluorescent in situ ... rare disease. Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes

    ... demonstrate peripheral blood cytopenia , bone marrow hypercellularity, and morphologically defined dysplasia of one or ...

    Research Article last updated 07/20/2018 - 5:15pm.