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  1. Th17 immune responses contribute to the pathophysiology of aplastic anemia.

    ... isolating Th17 cells from patients blood (n = 41) and bone marrow (BM) mononuclear cells (n = 7). The frequency and total number of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. The diagnosis and treatment of aplastic anemia: a review

    ... is a rare disorder characterized by suppression of bone marrow function resulting in progressive pancytopenia . A ... event-free survival to that in MSD HSCT. MUD HSCT post-IST failure proved to be a very good rescue strategy. Haploidentical donors/cord ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia

    ... unrelated non-human leukocyte antigen-matched bone marrow -derived mesenchymal stromal cells (MSCs) (median, 2.7 × 10(6) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... by pancytopenia associated with an empty or a fatty bone marrow. Historically the two treatments option have been immunosuppressive ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Unrelated cord blood transplantation in a child with very severe aplastic anemia

    ... Recently, bone marrow transplantation from an unrelated donor has been recommended ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... areas of general consensus, including the need for a bone marrow evaluation, cytogenetic and specific fluorescent in situ ... to IST, the time after IST initiation defining a treatment failure; use of hematopoietic growth factors; the preferred rescue therapy ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation.

    ... Journal Title:  Bone Marrow Transplant Primary Author:  ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Aplastic anemia: pathophysiology and treatment.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... poor outcome in older patients. The lack of a suitable bone marrow donor for all patients who need a transplant, illustrates the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Prognostic value of telomere attrition in patients with aplastic anemia.

    ... possible mechanistic insight into genomic instability of bone marrow cells derived from patients with critically short telomeres and/or ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... (HSC) and mesenchymal stem cells (MSC) affected graft failure and graft-versus-host disease (GVHD) in patients with severe ... colony-stimulating factor (G-CSF)-primed bone marrow and G-CSF-mobilized peripheral blood stem cells of haploidentical ...

    Research Article last updated 07/20/2018 - 5:15pm.