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  1. Myelodysplastic syndromes classification and risk stratification.

    ... Myelodysplastic syndromes (MDS) are spectrum of bone marrow failure disorders that share a common pathologic feature: cytologic ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Management of aplastic anemia: the role of systematic reviews and meta-analyses.

    ... Aplastic anemia is a rare bone marrow failure disorder. Allogeneic hematopoietic cell transplantation ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. SNP array-based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes.

    ... clonal aberrations may exist in some patients with bone marrow failure . Combined metaphase and SNP array karyotyping improved ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy.

    ... and organismal aging as well as in tumorigenesis. Bone marrow failure and malignancy are 2 life-threatening disease manifestations ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. STAT3-mutations indicate the presence of subclinical T cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.

    ... activation, responsible for the primary induction of bone marrow failure in a subset of AA and MDS patients. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia

    ... immune system and restoring hematopoiesis in bone marrow failure . Bone Marrow ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    ... aplastic anemia reported to the European Group for Blood and Marrow Transplantation. Between 1976 and 2009, 88 patients received 113 ... by posttransplant immunosuppression. Graft source was bone marrow in the majority of cases (n=77). Transplant practice changed ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... Journal Title:  Biol Blood Marrow Transplant Primary Author:  ... (SAA). We studied 1204 recipients of HLA-matched sibling bone marrow transplantation for SAA to determine whether HLA DR15 status ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Th17 immune responses contribute to the pathophysiology of aplastic anemia.

    ... isolating Th17 cells from patients blood (n = 41) and bone marrow (BM) mononuclear cells (n = 7). The frequency and total number of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. The diagnosis and treatment of aplastic anemia: a review

    ... is a rare disorder characterized by suppression of bone marrow function resulting in progressive pancytopenia . A ... event-free survival to that in MSD HSCT. MUD HSCT post-IST failure proved to be a very good rescue strategy. Haploidentical donors/cord ...

    Research Article last updated 07/20/2018 - 5:15pm.