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  1. Increasing the effectiveness of hematopoiesis in myelodysplastic syndromes: erythropoiesis-stimulating agents and transforming growth factor-β superfamily inhibitors

    ... of life, as well as iron overload due to red blood cell transfusion support. To promote proliferation and differentiation of ...

    Research Article last updated 10/02/2017 - 10:10am.

  2. Lenalidomide: Myelodysplastic syndromes with del(5q) and beyond

    ... to lenalidomide for the treatment of red blood cell transfusion -dependent anemia . Although lenalidomide has ...

    Research Article last updated 10/02/2017 - 9:54am.

  3. Ron Carlsen Beats Early Onset MDS; Grapples with Post-Transplant GVHD

    ... started to bruise easily with no explanation, and my red blood cell count started to drop. Eventually, I was put on epoetin alfa ... lenalidomide. By October 2006, I had become blood transfusion dependent, requiring one each week. The new problem was my ...

    Patient Chronicle last updated 07/25/2018 - 10:28am.

  4. SAA Patient Contributes to NIH Research

    ... I was 19 years old when I found out that I had low blood counts. At this time I was just starting college and also working three ... my blood counts, I started to get extremely sick and became transfusion dependent. My blood counts started to dramatically drop. I was very ...

    Patient Chronicle last updated 07/31/2018 - 1:14pm.

  5. What to Expect Before, During, and After a Blood Transfusion

    Before a Blood Transfusion Before a blood transfusion, a technician or nurse runs ...

    Page last updated 10/31/2014 - 2:35pm.

  6. Outcomes and healthcare utilization in children and young adults with aplastic anemia: A multiinstitutional analysis

    ... Journal Title:  Pediatr Blood Cancer Primary Author:  ... interval [CI] 0.6-2.58, P = 0.567), while every platelet transfusion was associated with higher mortality (OR 1.37, 95% CI ...

    Research Article last updated 07/18/2017 - 10:32am.

  7. Progress in Myelodysplastic Syndromes: Clinicopathologic Correlations and Immune Checkpoints

    ... The findings correlated with the recovery of peripheral blood counts and transfusion independency. CONCLUSION: BM morphology and PD-L1 ...

    Research Article last updated 09/11/2017 - 8:59am.

  8. Transfusion Thresholds, Quality of Life, and Current Approaches in Myelodysplastic Syndromes

    ... Hemoglobin thresholds and triggers for blood transfusions have changed over the years moving from a higher to a lower ... This review article summarizes the current evidence of transfusion thresholds in the hospitalized as well as in the outpatient setting ...

    Research Article last updated 06/23/2016 - 9:55am.

  9. Lenalidomide use in myelodysplastic syndromes: Insights into the biologic mechanisms and clinical applications

    ... by ineffective hematopoiesis leading to blood cytopenias and a variable risk of progression into acute myeloid ... of chromosome 5 (5q-), where it leads to high rates of transfusion independence and cytogenetic responses. Furthermore, ...

    Research Article last updated 02/21/2017 - 9:34am.

  10. How I treat acquired aplastic anemia

    ... Journal Title:  Blood Primary Author:  ... with immunosuppressive agents (IST), leading to transfusion independence , or complete recovery of peripheral blood counts, ...

    Research Article last updated 02/03/2017 - 9:51am.