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  1. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy and radiation ... (RA) or all IPSS categories if severe pancytopenia , transfusion requirements not responsive to therapy, or high risk ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  2. "You Can't Beat Me!"

    ... system. Taking ten different medications at one time and transfusion dependent, Derek missed a year of school. “I navigated ... people were added to the registry. By 2012, Derek’s blood counts returned to normal and he received his first Matthew ...

    Patient Chronicle last updated 04/25/2016 - 10:47am.

  3. RIC Transplant Using Haplo Donors

    ... greater; neutropenia or cytopenia requiring transfusion not responding to therapy; peripheral or BM blast count of <10%; ... Day 4. Other Name: Cytoxan Procedure: peripheral blood stem cell transplant Other Name: HSCT ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  4. Allo HSCT Using RIC for Hematological Diseases

    ... < 0.8, Anemia or thrombocytopenia requiring transfusion; Poor or very poor risk cytogenetics based on IPSS or R-IPSS ... to a fetus. Females of childbearing potential must have a blood test or urine study within 14 days prior to registration to rule out ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  5. MDS Diagnostic Spectrum

    ... scoring system for myelodysplastic syndromes . Blood. 2012:120(12):2454 WPSS Malcovati L et al. Time-dependent ... information from karyotype, platelet count and transfusion status. JCO 2011;29(4): 392. ...

    Topic section last updated 03/11/2016 - 12:23am.

  6. 2013 Scholarships Awarded to Special Group of Young People

    ... Soon afterwards, doctors noticed a drop in all three blood counts and by August, Kyle was diagnosed with aplastic anemia. One month ... the friend who sat by my side for my first blood transfusion and made me a charm bracelet to commemorate the occasion; my ...

    Page last updated 06/24/2015 - 10:22am.

  7. Clinical Trials Report for January 2016

    ... failure characterized by a requirement for red blood cell and platelet transfusions. Three different preparative ... is to evaluate the efficacy and safety of imetelstat in transfusion dependent participants with low or intermediate-1 risk ...

    Page last updated 01/07/2016 - 10:57am.

  8. Interviews with the Experts Managing MDS With Supportive Care and Active Treatment

    ... to giving a specific drug or agent that treats the disease. Blood transfusions are the backbone of supportive care for patients with MDS, ... If the counts improve, we keep these therapies going, with transfusion support as required especially in the initial phase of treatment. ...

    Interview last updated 09/22/2014 - 12:25pm.

  9. Immunosuppression and Stem Cell Transplantation – How Are These Treatments Chosen?

    ... who have been studied, has been useful in stimulating blood cell production. Eltrombopag is a growth factor , which was ... long term control of the disease, lessened the need for transfusion or even complete transfusion independent, and lessen the risk of ...

    Interview last updated 07/15/2015 - 10:19am.

  10. North American Pediatric Aplastic Anemia Consortium Symposium

    ... adults that causes the bone marrow to stop making blood cells.  As with all rare diseases, there is a relative lack of research ... Supportive care, which encompasses blood production transfusion and the prophylaxis and treatment of infections, is an important ...

    Page last updated 10/31/2013 - 4:06pm.