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  1. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... of using a system called CliniMACS to remove Tcells from blood stem cells . Removing T-cells may help stop a side effect called ... (MDS): RA//RARS/RCMD with high risk cytogenetic features or transfusion dependence as well as RAEB-1 and RAEB-2 and Acute myelogenous ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  2. Nursing Education Modules on MDS Disease Management and Patient Education

    ... – individualized therapy, minimal toxicity, improvement of blood counts, transfusion independence , delay of leukemic transformation, improved ...

    Page last updated 04/27/2015 - 2:44pm.

  3. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... recover faster following a stem cell transplant . Blood stem cells are very young blood cells that grow in the body to ... (MDS): RA/RCMD with high risk cytogenetic features or transfusion dependence, RAEB-1 and RAEB-2 Chronic myelomonocytic leukemia: ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  4. Heather Putney’s Trials (and Travels) with Aplastic Anemia

    ... to the gynecologist and a painless bruise led to a complete blood count draw, which showed markedly low platelets and hematocrit . ... anemia in the spring of 2012. Within two months, I was transfusion dependent for both red blood cells and platelets. In June, I was ...

    Patient Chronicle last updated 08/15/2016 - 8:42am.

  5. Clinical Trials Report for November 2014

    ... of this study is to see if selinexor will improve the blood counts and bone marrow function in people with your type of MDS. ... A Study of Aezea® (Cenersen) in Transfusion Dependent Anemia Associated With Myelodysplastic Syndrome (MDS) ...

    Page last updated 10/30/2014 - 9:42am.

  6. Clinical Trials Report for October 2014

    ... of this study is to see if selinexor will improve the blood counts and bone marrow function in people with your type of MDS. ... A Study of Aezea® (Cenersen) in Transfusion Dependent Anemia Associated With Myelodysplastic Syndrome (MDS) ...

    Page last updated 09/30/2014 - 10:05am.

  7. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders ... Blackfan Anemia (DBA) • other congenital transfusion dependent anemias Patients with sickle disease must have one or ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  8. MDS Drug Therapy

    ... sub-types of MDS Lenalidomide (Revlimid®) for transfusion-dependent MDS patients with isolated del(5q) and with a low or ... had some positive response to treatment, meaning that blood counts went up. The percentage of patients still surviving after two ...

    Topic section last updated 03/10/2016 - 11:26pm.

  9. ASH 2012 - Reviewing MDS Progress from Research and Clinical Perspectives

    ... (Procrit®) or darbepoetin (Aranesp®) work for low red blood cell counts. Romiplostin can be considered a platelet growth ... treated with romiplostin, based on prior platelet transfusion needs and blood levels of the hormone TPO. So just ...

    Interview last updated 02/07/2013 - 1:28pm.

  10. Infections in myelodysplastic syndromes: a review

    ... by transiently worsening the pre-existing low white blood cell (WBC) counts. However, this increased risk of infections ... and liver disease and particularly those with greater transfusion needs are most vulnerable to infections. Available data from two ...

    Research Review last updated 05/02/2016 - 9:28am.