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  1. Treatments

    ... mature Increase the number of healthy cells in your blood Kill abnormal bone marrow cells  Reduce the number of  ... A blood transfusion is a safe and common procedure. Most people who have a bone ...

    Topic section last updated 08/07/2018 - 2:28pm.

  2. SAA Patient Contributes to NIH Research

    ... I was 19 years old when I found out that I had low blood counts. At this time I was just starting college and also working three ... my blood counts, I started to get extremely sick and became transfusion dependent. My blood counts started to dramatically drop. I was very ...

    Patient Chronicle last updated 07/31/2018 - 1:14pm.

  3. The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes

    ... associated with transfusions, chronic anemia and red blood cell (RBC) transfusion dependence impact negatively on survival and quality of life (QoL), ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... the response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal Nocturnal ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. The immunomodulatory agents lenalidomide and thalidomide for treatment of the myelodysplastic syndromes: A clinical practice guideline.

    ... with the aging population. Treatment includes red blood cell transfusion for anemia . The immunomodulatory agents (imids) ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Self-perception of symptoms of anemia and fatigue before and after blood transfusions in patients with myelodysplastic syndromes

    ... anemia . Many patients with MDS are dependent on regular blood transfusions. The study aimed to investigate symptoms of anemia and ... in patients with MDS immediately before and after blood transfusion and to capture patients' descriptions of their symptoms. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Blood stream infection after stem cell transplantation in children with idiopathic aplastic anemia

    ... Journal Title:  Biol Blood Marrow Transplant Primary ... transplantation from unrelated donors, frequent blood transfusion before transplantation, major or major+minor mismatch of ABO ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab.

    ... Previously, we described short-term improvements in blood counts in two pilot studies treating moderate aplastic anemia (mAA) and ... achieved long-term packed red blood cell PRBC transfusion independence , and all PRCA responders achieved long-term ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Durable long-term responses in patients with myelodysplastic syndromes treated with lenalidomide.

    ... has proven efficacy and safety and has been shown to reduce transfusion requirements and reverse cytogenetic abnormalities in lower-risk ... of these patients had an ongoing requirement for red blood cell transfusions despite previous treatment with recombinant ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

    ... endogenous erythropoietin levels and limited red blood cell transfusion history can predict response to erythropoiesis-stimulating agents ... Variables including baseline endogenous THPO levels, transfusion needs, and platelet response were analysed in a randomized trial ...

    Research Article last updated 07/20/2018 - 5:15pm.