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  1. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... leukemia or myelodysplasia with no circulating blasts and with less than 5% blasts in the bone marrow . Patients with chronic lymphocytic ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  2. FAQs

    ... cells in your bone marrow being young white blood cells ( blasts ). About 30 out of 100 people with MDS will develop AML. Certain ... you have 3. Percentage of young white blood cells ( blasts ) in your bone marrow. 4. The number of cytogenetic changes you ...

    Topic section last updated 03/02/2016 - 11:42am.

  3. Azacitidine and Lenalidomide for Relapsed and Refractory Patients With Acute Myeloid Leukemia

    ... criteria21: Relapsed: Bone marrow blasts ≥5%; reappearance of blasts in the blood; development of extramedullary disease Refractory ...

    Clinical Trial last updated 06/06/2016 - 1:30pm.

  4. MEDALIST Trial

    ... < 15%) if SF3B1 mutation is present. - < 5% blasts in bone marrow - Peripheral blood WBC count < 13,000/μL ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  5. Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

    ... cells in the peripheral blood Less than 30% marrow blasts Absence of t(9:22) or BCR-ABL transcript Adequate major ...

    Clinical Trial last updated 07/14/2016 - 3:59pm.

  6. UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    ... Must be in remission by morphology (<5% blasts ). Note cytogenetic relapse or persistent disease without morphologic relapse is acceptable. Also a small percentage of blasts that is equivocal between marrow regeneration vs. early relapse are ...

    Clinical Trial last updated 04/29/2016 - 10:06am.

  7. MDS is a Complicated Group of Disorders

    ... cases MDS progresses from lower- risk to higher-risk as blasts (immature white blood cells) increase in the bone marrow .  When the percentage of blasts reaches 20% or more, the patient is diagnosed as having acute ...

    Page last updated 06/27/2012 - 1:51pm.

  8. Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

    ... AML) as documented by the presence of >20% myeloid blasts in the bone marrow Subjects must be 18 years of age and ...

    Clinical Trial last updated 06/13/2016 - 3:24pm.

  9. Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

    ... syndrome (MDS) (defined as having >/= 10% blasts in the bone marrow ) or patients with Chronic Myelomonocytic Leukemia (CMML) (having >/= 10% blasts in the bone marrow) may also be eligible after discussion with Principal ...

    Clinical Trial last updated 05/23/2016 - 3:37pm.

  10. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... Disease status: remission or <10% bone marrow blasts Myelodysplasia Acute lymphoblastic leukemia Disease status: ...

    Clinical Trial last updated 06/06/2016 - 3:10pm.