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  1. Allogeneic stem cell transplantation in myelodysplastic syndromes: does pretransplant clonal burden matter?

    ... Although patients who undergo alloSCT with excess blasts have poorer outcomes than those transplanted with fewer blasts, the effect of clone size in patients with MDS without increased ...

    Research Article last updated 04/29/2016 - 10:22am.

  2. Are Myelodysplastic Syndromes Underdiagnosed in Poland? A Report by the Polish Adult Leukaemia Group

    ... with MDS and acute myeloid leukaemia (AML) with 20-29% blasts were enrolled. Data collection was conducted for strictly predefined ...

    Research Article last updated 11/02/2016 - 10:17am.

  3. Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial

    ... in patients with myelodysplastic syndromes with excess blasts after failure of azacitidine or decitabine ... with diagnosis of refractory anaemia with excess blasts (RAEB)-1, RAEB-2, RAEB-t, or chronic myelomonocytic leukaemia based on ...

    Research Article last updated 06/07/2016 - 11:10am.

  4. TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes

    ... 53 (46%) had bone marrow blast clearance (<5% blasts ). Response rates were higher among patients with an unfavorable-risk ...

    Research Article last updated 01/26/2017 - 10:07am.

  5. Comparative clinical effectiveness of azacitidine versus decitabine in older patients with myelodysplastic syndromes

    ... to patients with refractory anaemia with excess blasts (RAEB). In 2025 HMA-treated patients, median survival was 15 months ...

    Research Article last updated 10/06/2016 - 11:34am.

  6. Myelodysplastic syndromes: Contemporary review and how we treat

    ... peripheral blood and bone marrow dysplasia/ blasts , and clonal cytogenetic abnormalities. With the advent of next ...

    Research Article last updated 04/29/2016 - 1:05pm.

  7. A Meta-Analysis of the Relationship between Cigarette Smoking and Incidence of Myelodysplastic Syndromes.

    ... with ringed sideroblasts (RARS) or RA with excess blasts (RAEB)/RAEB in transformation (RAEBt), respectively. Our results ...

    Research Article last updated 04/29/2016 - 12:57pm.

  8. Personalized medicine for MDS

    ... who does not require transfusions, has no increase in blasts , nor any poor-risk cytogenetic abnormalities. These patients, ...

    Research Review last updated 05/02/2016 - 9:44am.

  9. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... or relapse/ refractory less than or equal to 10% blasts in bone marrow , or aplasia post-therapy. This includes ... in CR, or relapse with less than or equal 10% bone marrow blasts. CML with tyrosine kinase inhibitor failure in chronic or ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  10. Understanding Prognosis in MDS

    ... help determine prognosis—the percentage of bone marrow blasts (immature white blood cells), the number of cytopenias (low blood ... to help determine prognosis—the percentage of bone marrow blasts (immature white blood cells), the number of cytopenias (low blood ...

    Interview last updated 05/02/2012 - 4:36pm.