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  1. Acute Myeloid Leukemia (AML)

    ... of every 100 white blood cells in the bone marrow is a blast cell . AML is the most common acute leukemia affecting adults, with about ...

    Topic section last updated 10/08/2018 - 7:10pm.

  2. Myelodysplastic Syndromes (MDS)

    ... Blast Counts Blasts are very young or ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia . ...

    Page last updated 09/14/2018 - 2:43pm.

  3. Allogeneic hematopoetic stem cell transplantation in pediatric myelodysplastic syndromes: Improved outcomes for de novo disease.

    ... Allogeneic hematopoetic stem cell transplantation in pediatric myelodysplastic syndromes : Improved ... p = 0.02). There was no correlation of survival with blast count at diagnosis, IPSS score, cytogenetic abnormality, donor type, or ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes

    ... Allogeneic hematopoietic stem cell transplantation (alloSCT) is currently the only curative treatment ... two groups (P = 0.500). However, for patients with a high blast count (>5 % of bone marrow at the time of diagnosis), ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. MDS - Basics

    ... Blast Counts Blasts are very young ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia ...

    Topic section last updated 06/12/2018 - 12:47pm.

  6. Myelodysplastic syndromes in children: where are we today?

    ... and Down syndrome-associated myeloid leukemia.Although the blast count plays a central role in differentiating leukemias from MDSs, it is ... when detected make diagnosis easy. Hematopoietic stem cell transplant is the treatment of choice, while newer agents have shown ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

    ... (MDS) fare poorly following allogeneic hematopoietic cell transplant (HCT). We report prospective phase II study results of 29 ... and blasts <10%). Marrow cellularity (P<0.0001) and blast% (P=0.03) were reduced. Toxicities were acceptable, with transient ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

    ... chronic myelomonocytic leukaemia ( white blood cell count <13 000/μL), and had anaemia with or without red blood ... in one patient each: myalgia (one [2%]), increased blast cell count (one [2%]), and general physical health deterioration (one ...

    Research Article last updated 09/18/2017 - 1:38pm.

  9. An Unusual Route to Diagnosis

    ... , hematocrit , and my red and white blood cell count. She ran several tests, and I had a liver biopsy.  After a ... doctors consulted with each other it was determined that my blast count (young, immature white blood cells was better than expected so we ...

    Patient Chronicle last updated 04/26/2018 - 12:12pm.

  10. Diseases

    ... the bone marrow and interfere with the body’s normal blood cell production. ... that have an abnormal shape, size or look. These are called blast cells. Most experts agree that MDS is a form of blood and bone marrow ...

    Page last updated 10/08/2018 - 5:10pm.