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  1. Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

    ... years. Adequate organ function defined as: Bilirubin ≤1.5 x upper limit of normal (ULN) ALT ≤ 3 x ULN and AST ...

    Clinical Trial last updated 06/06/2016 - 10:04am.

  2. A Study of E6201 for the Treatment of Advanced Hematologic Malignancies With FLT3 Mutation (AML)

    ... creatinine clearance ≥ 4 mL/minute total bilirubin ≤ 2 times the upper limit of normal (ULN) unless due to ...

    Clinical Trial last updated 05/09/2016 - 4:09pm.

  3. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... CT scan to determine pulmonary status. Total bilirubin ≤ to 1.5 ULN (unless benign congenital elevated bilirubin); ALT/ AST ≤ 2.5 x upper limit of normal (ULN). Calculated ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  4. Prior allogeneic transplant Karnofsky Performance Score < 70% Active central nervous system (CNS) involvement by malignant cells Patients with uncontrolled bacterial, viral or fungal infections (currently taking medication and with progre

    ... =< 1.7 mg/dL (males age >= 16 years) Total bilirubin =< 1.5 x upper limit of normal (ULN) for age Serum glutamic ...

    Clinical Trial last updated 06/06/2016 - 2:05pm.

  5. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... < 2.5 x ULN, unless elevated secondary to disease. Total bilirubin < 2 x ULN (patients with Gilbert's syndrome may be included at ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  6. Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET)

    ... AST and ALT < 2 x upper limit of normal Total bilirubin within normal limits ... AST and ALT > 2 x upper limit of normal Total bilirubin > 1.5 mg/ml No detectable PNH ( paroxysmal nocturnal ...

    Clinical Trial last updated 04/29/2016 - 9:59am.

  7. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... organ and marrow function as defined below: Serum bilirubin < 2.0mg/dL ALT(SGPT) 3 X upper limit of normal Creatinine ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  8. SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)

    ... Serum albumin ≥3.0 g/dL (or ≥30 g/L) Bilirubin ≤1.5 mg/dL (or ≤26 µmol/L) Aspartate transaminase (AST) ...

    Clinical Trial last updated 06/06/2016 - 2:11pm.

  9. Phase I, Dose Escalation Study of Decitabine

    ... (ALT) greater than 3 times normal or serum total bilirubin greater than 2 mg/dL; ...

    Clinical Trial last updated 06/06/2016 - 9:44am.

  10. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... organ function defined as the following: Total bilirubin ≤ upper limit of normal (ULN) for age, or if total bilirubin is > ULN, direct bilirubin is ≤ 1.5 mg/dL AST (SGOT)/ALT (SGPT) ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.