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  1. Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

    ... detectable CH50 activity (CH50>10%) (p=0.004), elevated bilirubin levels (p<0.0001), and the need for transfusions (p=0.034). This ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. A retrospective study of paroxysmal nocturnal hemoglobinuria in pediatric and adolescent patients

    ... first group of patients had higher levels of LDH, total bilirubin and absolute reticulocyte count and a bigger PNH ...

    Research Article last updated 05/02/2017 - 10:42am.

  3. FDA approves new drug for relapsed or refractory AML

    ... of patients were nausea, vomiting, diarrhea, elevated bilirubin , and decreased appetite. Differentiation syndrome occurred in 14% ...

    Article last updated 08/30/2017 - 8:30am.

  4. A Phase II Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms

    ... have normal organ function as defined below: Total bilirubin < or = 1.5 x institutional upper limit of normal unless ...

    Clinical Trial last updated 05/14/2018 - 2:02pm.

  5. Diagnosis

    ... with PNH to have LDH monitored regularly. A bilirubin test measures the total amount of this substance in your blood. ...

    Topic section last updated 03/10/2016 - 11:04pm.

  6. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... by: Hepatic: < 3x ULN ALT and < 1.5 total serum bilirubin , unless there is congenital benign hyperbilirubinemia. Renal: ... by: Hepatic: < 3x ULN ALT and < 1.5 total serum bilirubin , unless there is congenital benign hyperbilirubinemia. Renal: ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  7. A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients with Myelodysplastic Syndrome (MDS)

    ... be calculated per institutional standard. Serum total bilirubin 1.5 ULN. AST (SGOT) and ALT (SGPT) Female subject of ...

    Clinical Trial last updated 05/14/2018 - 1:57pm.

  8. AML Therapy With Irradiated Allogeneic Cells

    ... of AML in patient >= 60 years old Total bilirubin =< 1.5 times upper limit of normal (ULN) institutional limits ... of patient adverse effects or poor outcomes Total bilirubin < 1.5 times upper limit of normal (ULN) institutional limits (unless ...

    Clinical Trial last updated 06/13/2016 - 3:14pm.

  9. Fludarabine/Clofarabine/Busulfan Combined With SAHA in Acute Leukemia

    ... Estimated creatinine clearance at least 50 ml/min. Bilirubin equal or less than 1.5 (unless Gilbert's Syndrome), SGPT <3 X ...

    Clinical Trial last updated 06/06/2016 - 11:07am.

  10. Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS (AML)

    ... Oncology Group performance status 0, 1, or 2 Total bilirubin ≤ 2 Serum aspartate aminotransferase (AST) and alanine ...

    Clinical Trial last updated 05/02/2016 - 11:06am.