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  1. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... Allogeneic stem cell transplantation (SCT) is the only therapeutic modality at present ... optimal choice of transplant conditioning intensity in MDS. Autologous SCT has been extremely investigated in MDS. It is limited to ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Explaining SCT vs. Cellular Therapies

    ... Article Link:  Stem Cell Transplants and Cellular Therapies: What’s the Difference? ... patient’s own stem cells are used – an approach known as autologous transplant – the chemotherapy and/or radiation therapy are ...

    Article last updated 09/08/2017 - 12:41pm.

  3. MEDALIST Trial

    ... ferritin ≤ 15 μg/L  Prior allogeneic or autologous stem cell transplant Known history of diagnosis of Acute myeloid ...

    Clinical Trial last updated 02/22/2017 - 11:42am.

  4. Recent developments in bone marrow transplants

    ... lenalidomide (Revlimid, Celgene) maintenance following autologous hematopoietic stem cell transplantation improved survival outcomes without increasing the ...

    Article last updated 11/16/2016 - 2:56pm.

  5. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... immediately Research participants must have a donor or stem cell source identified for allogeneic transplantation, either related (7/8 ... CD123-CAR/CD28-costimulatory, lentiviral vector-transduced autologous T lymphocytes Given IV Other Name: CD123R(EQ)28zeta/EGFRt+ ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  6. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... of chemotherapy and radiation before giving the stem cells . However, high doses of chemotherapy and radiation can have ... marrow involvement and therefore are not suitable for an autologous transplant OR have failed an autologous transplant and be in ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  7. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... guideline for HLA -Haploidentical hematopoietic stem cell transplant (HSCT) using a reduced intensity conditioning (RIC) ... that has failed or patients who are ineligible for an autologous transplant. Chronic lymphocytic leukemia/small lymphocytic ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  8. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... this study is to find out whether the addition of blood stem cells from a close family member, when added to two units of umbilical ... prior stem cell transplants of any kind. One prior autologous stem cell transplant within the preceding 12 months. One ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  9. Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

    ... refractory disease, or relapse (including relapse post autologous hematopoietic stem cell transplant ). Double hit lymphomas in first remission or more ...

    Clinical Trial last updated 06/06/2016 - 12:58pm.

  10. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... third complete remission, or relapse (including relapse post autologous hematopoietic stem cell transplant ). Relapsed double hit lymphomas. Patients with options ...

    Clinical Trial last updated 06/06/2016 - 10:28am.