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  1. Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia

    ... life-threatening consequence of treatment for autoimmune disease (AID) and an emerging clinical phenomenon. Objective   To ...

    Research Article last updated 02/03/2017 - 1:25pm.

  2. Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

    ... for the maintenance of functional immunity. Hallmarks of autoimmune disease pathogenesis are abnormal CD4(+) and CD8(+) T cell ...

    Research Article last updated 04/29/2016 - 12:59pm.

  3. Causes

    ... aplastic anemia is usually considered an autoimmune disease . Normally, your immune system attacks only foreign substances. When ...

    Topic section last updated 07/20/2018 - 5:15pm.

  4. Simona Pagliuca, MD

    ... Aplastic anaemia, is a rare disease in which the bone marrow and the hematopoietic stem cells ... of hematopoietic stem cells by an aberrant autoimmune attack. Allogeneic hematopoietic stem cell transplantation ...

    Grant Recipient last updated 08/15/2018 - 12:22pm.

  5. Isabel Mérida, PhD

    ... Aplastic anemia is a disease in which the bone marrow gradually stops producing red and ... some cases, T cells attack the cells from the body, causing autoimmune diseases like lupus or rheumatoid arthritis. Patients with ...

    Grant Recipient last updated 07/05/2018 - 11:17am.

  6. A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients with Myelodysplastic Syndrome (MDS)

    ... Bone Marrow Disease(s):  myelodysplastic syndromes (MDS) ... heart failure, angina pectoris or cardiac arrhythmia and autoimmune processes that in the opinion of the investigator would make the ...

    Clinical Trial last updated 05/14/2018 - 1:57pm.

  7. Strong results for SAA patients at Johns Hopkins

    ... 16 aplastic anemia patients free of disease after bone marrow transplant and chemo ... blood transfusions, take multiple medicines to suppress the autoimmune response that damages the marrow, take other drugs to prevent ...

    Article last updated 02/07/2017 - 11:05am.

  8. Retired MDS Patient Living Life to the Fullest Since Transplant

    ... multiple post-transplant problems such as graft versus host disease and four compression fractures from the steroids. But I was alive, ... the mouth and skin. It has progressed to scleroderma, an autoimmune disease characterized by hardening of the skin.  But, with the ...

    Patient Chronicle last updated 04/26/2018 - 10:43am.

  9. The immune landscape of myelodysplastic syndromes

    ... review we will first describe the clinical and laboratory autoimmune manifestations often detectable in MDS patients. We will then focus ... influence of different immune cell subpopulations on the disease onset and evolution. We will finally consider therapeutic approaches ...

    Research Article last updated 11/28/2016 - 9:37am.

  10. Myelodysplastic Syndromes in Adolescent Young Adults: One Institution's Experience

    ... patients, aged 18 to 39 years, possibly reflecting different disease biology. Myelodysplastic syndrome (MDS) is mainly a disease of the ... more circulating myeloblasts, and more hypoplastic MDS. Autoimmune disorders were more prevalent in older patients. The median overall ...

    Research Article last updated 09/19/2016 - 11:09am.