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  1. Retrospective survey on the prevalence and outcome of prior autoimmune diseases in patients with aplastic anemia reported to the registry of the European group for blood and marrow transplantation.

    ... anemia (AA) is rarely described after a diagnosis of autoimmune disease (aID). AIMS: To assess the prevalence of prior aID in ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Myelodysplastic Syndromes (MDS) and autoimmune disorders (AD): Cause or consequence?

    ... are frequently associated with clinical manifestations of autoimmune disorders (AD) and inflammatory response of the immune system. AD ... a high proportion of those patients MDS is diagnosed during disease course. Antinuclear antibodies (ANA) are frequently found among MDS ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Epidemiology and risk factors for infections in myelodysplastic syndromes.

    ... 95% CI = 1.2-2.7, P < 0.007), chronic obstructive pulmonary disease (HR = 2.6, 95% CI = 1.4-4.9, P < 0.003), history of other malignancy (HR 2.0, 95% CI = 1.3-3.1, P < 0.003), and autoimmune disease (HR 2.9, 95% CI = 1.4-6.0, P < 0.005). Age, nadir ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Mayo Clinic links MDS with autoimmune drug

    ... Mayo Clinic: Association between autoimmune disease and bone marrow disorders ...

    Article last updated 02/03/2017 - 1:19pm.

  5. Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia

    ... Acquired aplastic anemia (aAA) is a nonmalignant disease caused by autoimmune destruction of early hematopoietic cells. Clonal hematopoiesis ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Th17 immune responses contribute to the pathophysiology of aplastic anemia.

    ... production of interleukin-17 (IL-17) and association with autoimmune diseases. We studied the role of Th17 cells in aplastic anemia ... (P = .0007 and .02, respectively) and correlated with disease activity. There was an inverse relationship between the numbers of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients.

    ... bone marrow failure syndrome, caused by autoimmune destruction of hematopoietic stem and progenitor cells. ... exposures and metabolic gene polymorphisms contribute to disease pathogenesis. Several case-control studies linked homozygous deletion ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Rabbit-antithymocyte globulin combined with cyclosporin A as a first-line therapy: improved, effective, and safe for children with acquired severe aplastic anemia.

    ... Acquired aplastic anemia is an organ-specific auto-immune disease characterized by pancytopenia and hypoplastic bone marrow ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Are T-cell dysfunctions the other side of the moon in the pathogenesis of myelodysplastic syndromes?

    ... review, we will first describe the clinical and laboratory autoimmune manifestations often detectable in MDS patients. We will then focus ... of T-cell activation and their implications in the disease history. The potential impact of specific cell subsets, such as ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia

    ... life-threatening consequence of treatment for autoimmune disease (AID) and an emerging clinical phenomenon. Objective: To ...

    Research Article last updated 02/21/2017 - 10:55am.