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  1. Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia

    ... aplastic anemia (AA) who are refractory to anti-thymocyte globulin (ATG) and cyclosporine , a second course of immunosuppression ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Eltrombopag in aplastic anemia

    ... is currently with immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG) and cyclosporine , to which two thirds of patients ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... regimen consisted of BU, fludarabine , CY and anti-thymocyte globulin. All patients received cyclosporine , short-term MTX, ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... AlloHSCT approach, using fludarabine and anti-thymocyte globulin based conditioning with high (200 mg/kg) and low (60 mg/kg) dose ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Aplastic anemia: what have we learned from animal models and from the clinic.

    ... of responsiveness of AA to immunomodulatory agents such as anti-thymocyte globulin (ATG) and the requirement of cyclosporine to maintain ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... with AA include: (1) immunosuppressive therapy (IST) with anti-thymocyte globulin and cyclosporine A which targets self-reactive T cells, or (2) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Allogeneic stem cell transplantation using alemtuzumab-containing regimens in severe aplastic anemia.

    ... low incidence of GVHD makes it an attractive alternative to anti-thymocyte globulin (ATG) in transplant conditioning regimen for severe aplastic anaemia ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Outcome of patients activating an unrelated donor search for severe acquired aplastic anemia.

    ... sibling donor receive immunosuppressive treatment (IST) with anti-thymocyte globulin (ATG). In the case of no response to IST, a voluntary unrelated ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Engraftment of heavily transfused patients with severe aplastic anemia with a fludarabine-based regimen

    ... We have developed a practical conditioning regimen without anti-thymocyte globulin (ATG), irradiation, or other myeloablative alkylating agent for ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Front-line immunosuppressive treatment of acquired aplastic anemia

    ... briefly illustrated. First-line IST should consist of horse anti-thymocyte globulin (ATG) and CsA that has been shown to result in response rates between ...

    Research Article last updated 07/20/2018 - 5:14pm.