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  1. Unrelated cord blood transplantation in a child with very severe aplastic anemia

    ... as an option for the treatment of very severe aplastic anemia (vSAA) refractory to immunosuppressive therapy (IST) in the ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP)

    ... Acquired aplastic anemia (AA) is a rare heterogeneous disease characterized by ... but higher in East Asia. Survival in severe aplastic anemia (SAA) has markedly improved in the past 2decades because of advances in ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Aplastic anemia: pathophysiology and treatment.

    ... An immune basis for most patients with aplastic anemia (AA) provides a rationale for immunosuppressive therapy (IST), ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    ... Aplastic anemia is usually treated with immunosuppression or allogeneic transplant, ... analysis of all syngeneic transplants for aplastic anemia reported to the European Group for Blood and Marrow Transplantation. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels

    ... from unrelated donors in patients with severe aplastic anemia . All patients received fixed doses of antithymocyte globulin ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Asymptomatic cerebral bleeds in patients with aplastic anemia.

    ... We investigated 26 newly diagnosed patients of aplastic anemia (AA) with GE-MRI of brain who were otherwise neurologically ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. The complex pathophysiology of acquired aplastic anemia

    ... in the pathophysiology of acquired aplastic anemia (aAA). Dysregulated CD8+ cytotoxic T cells, CD4+ T cells including ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Current outcome of HLA identical sibling vs. unrelated donor transplants in severe aplastic anemia: an EBMT analysis

    ... We have analyzed 1448 patients with acquired aplastic anemia , grafted between 2005 and 2009, and compared outcome of identical ... of unrelated donor transplants for acquired aplastic anemia, is currently not statistically inferior when compared to sibling ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Effect of stem cell source on outcomes after unrelated donor transplantation in severe aplastic anemia

    ... bone marrow (BM) transplantation for severe aplastic anemia (SAA) has improved, with survival rates now approximately 75%. ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Survival of patients with documented autologous recovery after SCT for severe aplastic anemia: a study by the WPSAA of the EBMT.

    ... BMT (hematopoietic SCT (HSCT)) for severe aplastic anemia (SAA) and the prognosis is poor. The recovery of host- ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 07/20/2018 - 5:14pm.