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  1. Recipient-derived EBV-positive Monomorphic Plasmacytoma Type Posttransplant Lymphoproliferative Disorder After Allogeneic Stem Cell Transplant for Severe Aplastic Anemia: A Case Report

    ... (PTLD) has not been reported after pediatric hematopoietic stem cell transplantation. We present a child with hepatitis-associated severe aplastic anemia who underwent an unrelated allogeneic hematopoietic stem cell transplantation and subsequently developed ...

    Research Article last updated 11/01/2016 - 1:50pm.

  2. Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation.

    ... Although hematopoietic stem cell transplantation (HSCT) with a conditioning regimen consisting of ...

    Research Article last updated 05/22/2017 - 10:32am.

  3. Making Progress for Myelodysplastic Syndromes

    ... we tailor therapy based on that, such as recommending allogeneic stem cell transplant for patients. An accurate risk assessment for the ...

    Article last updated 07/26/2017 - 10:25am.

  4. Allogeneic hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: a retrospective single-center study

    ... (PNH) is a rare clonal disease of hematopoietic stem cell characterized by complement mediated intravascular hemolysis . ...

    Research Article last updated 11/02/2016 - 10:41am.

  5. Comparison of Intensive Chemotherapy and Hypomethylating Agents before Allogeneic Stem Cell Transplantation for Advanced Myelodysplastic Syndromes: A Study of the Myelodysplastic Syndrome Subcommittee of the Chronic Malignancies Working Party of the Europ

    ... conventional chemotherapy (CC) before hematopoietic stem cell transplantation (HSCT) in 209 patients with advanced myelodysplastic ...

    Research Article last updated 07/18/2016 - 11:22am.

  6. Allogeneic stem cell transplantation in myelodysplastic syndromes: does pretransplant clonal burden matter?

    ... therapy for myelodysplastic syndromes (MDS) is allogeneic hematopoietic stem cell transplantation (alloSCT). As alloSCT confers both a short-term mortality ...

    Research Article last updated 04/29/2016 - 10:22am.

  7. Major news in BMT with half-match donors

    ... Texan is first adult in U.S. to receive updated stem cell transplant for leukemia treatment ... that serves patients who develop this complication after an allogeneic transplantation. UT Southwestern’s Simmons Cancer Center is ...

    Article last updated 06/14/2016 - 3:02pm.

  8. New positive results for GVHD treatment

    ... treat a common and serious complication of a type of stem cell transplant , findings from a small clinical trial show. ... transplant of donated blood stem cells , known as an allogeneic transplant. The patients’ symptoms—including widespread skin ...

    Article last updated 01/12/2017 - 11:10am.

  9. Drug reduces acute GVHD in unrelated HSCTs

    ... donor myeloablative conditioning hematopoietic stem cell transplant (HSCT).1 In a phase II single-arm study, the ... a significant barrier to a more widespread application of allogeneic HSCT for patients with hematologic malignancies. Vorinostat is a ...

    Article last updated 02/27/2017 - 1:45pm.

  10. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... not eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including ... of >30%) d.         Suitable candidate to receive allogeneic stem cell transplantation; patient is eligible for study if a ...

    Clinical Trial last updated 05/04/2018 - 3:53pm.