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  1. Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes

    ... Allogeneic hematopoietic stem cell transplantation (alloSCT) is currently the only curative treatment ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Can G-CSF Cause Leukemia in Hematopoietic Stem Cell Donors?

    ... A large majority of allogeneic hematopoietic stem cell donations are achieved using granulocyte -colony stimulating ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    ... anemia is usually treated with immunosuppression or allogeneic transplant, depending on patient and disease characteristics. ... and anti-thymocyte globulin as well as peripheral blood stem cells performed in later years. Ten year overall survival was 93% with ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... Allogeneic stem cell transplantation (SCT) is the only therapeutic modality at present ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Laboratory tests for paroxysmal nocturnal hemoglobinuria (PNH).

    ... Glycan class A (PIG-A) gene in the hematopoietic stem cells (HSC) of patients. The presence of these mutations leads to ... C5 ( Eculizumab ), anticoagulation, and in some cases allogeneic HSC transplant. In this paper we review the different diagnostic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Transplantation for myelodysplastic syndromes 2013.

    ... patients with myelodysplastic syndromes (MDS) is allogeneic haematopoietic stem cell transplantation (HCT). However, many MDS patients are older, often ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... Cyclophosphamide -based conditioning regimens and allogeneic hematopoietic stem cell transplantation (AlloHSCT) from matched related donors (MRD) has ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Optimizing management of myelodysplastic syndromes post-allogeneic transplantation

    ... Allogeneic hematopoietic stem cell transplantation is still the only potentially curative treatment for ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Less could be better: The case for reducing the dose of cyclophosphamide for children undergoing allogeneic stem cell transplant for severe aplastic anemia.

    ... Journal Title:  Pediatr Transplant Primary Author:  ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Patient selection for transplantation in the myelodysplastic syndromes.

    ... Allogeneic hematopoietic stem cell transplantation remains the only known curative procedure for the ...

    Research Article last updated 07/20/2018 - 5:14pm.