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  1. Targeting immune dysregulation in myelodysplastic syndromes.

    ... After treatment with a clinical protocol using alemtuzumab , an anti-CD52 antibody, her blood cell counts returned to ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.

    ... all, 28/29 proceeded to transplant; 27 received ATG or alemtuzumab . Post HCT, 180 day non-relapse mortality (NRM) was 7% (95% ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. The diagnosis and treatment of aplastic anemia: a review

    ... or alternative immunosuppressive therapies, such as alemtuzumab , may represent valid tools for resistant/relapsing cases. New ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Management of the refractory aplastic anemia patient: what are the options?

    ... is only around 30-35%. Response may also occur with alemtuzumab or the thrombopoietin mimetic, eltrombopag , in ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Management of the refractory aplastic anemia patient: what are the options?

    ... is only ∼ 30% to 35%. Response may also occur with alemtuzumab or the thrombopoietin mimetic eltrombopag in refractory ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Aplastic anemia: therapeutic updates in immunosuppression and transplantation

    ... and cyclosporine . More recently, the role of alemtuzumab in SAA has been better defined and an oral thrombomimetic, ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Immunological derangement in hypocellular myelodysplastic syndromes

    ... , anti-thymocyte globulin and/or cyclosporine, or alemtuzumab . Here we review all these immune mechanisms as well as the ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Evaluation of efficacy of alemtuzumab in 5 patients with aplastic anemia and/or myelodysplastic neoplasm

    ... therapy, including the anti-CD52 antibody alemtuzumab . We analyzed treatment responses to alemtuzumab in 5 patients with MDS or aplastic anemia (AA) evolving to MDS. ...

    Research Article last updated 11/01/2016 - 1:56pm.

  9. Rational Management Approach To Pure Red Cell Aplasia

    ... in hypogammaglobulinemia cases. In salvage settings, alemtuzumab is active, particularly in large granular lymphocytic leukemia ... salvage agents such as intravenous immunoglobulin, alemtuzumab and bortezomib. LINK to Journal ...

    Research Article last updated 12/14/2017 - 10:12am.

  10. Eltrombopag for the treatment of aplastic anemia: current perspectives

    ... globulin, high-dose cyclophosphamide , and alemtuzumab . Eltrombopag , a thrombopoietin mimetic, has recently ...

    Research Article last updated 11/01/2016 - 2:01pm.