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  1. Stem Cell Transplantation: What Happens Behind the Scenes?

    ... a patient all the way from first referral for a stem cell transplant right through the transplant itself. They’re the ... the exact same typing.  That means that many people don’t have a sibling match, so we look in the Be the Match® registry.  The ...

    Interview last updated 01/18/2018 - 1:28pm.

  2. I’m working through aplastic anemia – my son helps me keep focused.

    ... started bleeding. I hoped this would stop, but that didn’t happen. Finally, when I was attending a local football game, one side of my ... is a half-matched donor. My approval for a stem cell transplant at National Institutes of Health (NIH) came recently. I ...

    Patient Chronicle last updated 01/11/2018 - 9:55am.

  3. Emerging Therapeutics for the Control of Chronic Graft-versus-Host Disease

    ... mortality and morbidity after allogeneic hematopoietic stem cell transplantation (SCT). In parallel with an increased use of ... facets of adaptive and innate immunity, including B cells, T cells, and macrophages and their interactions with target tissue. ...

    Research Article last updated 01/04/2018 - 2:44pm.

  4. Rational Management Approach To Pure Red Cell Aplasia

    ... Pure red cell aplasia is an orphan disease without rationally established standard ... There is overlap between idiopathic cases and those with T-large granular lymphocytic leukemia, hypogammaglobulinemia, and low-grade ...

    Research Article last updated 12/14/2017 - 10:12am.

  5. Sicheng Wen, MD, PhD

    ... Reversal of aplastic anemia by mensenchymal stem cell-derived extracellular vesicles ... Aplastic anemia is a blood disorder where the body doesn't make enough blood cells. Marrow transplantation, antithymocyte globulin ...

    Grant Recipient last updated 01/05/2018 - 1:09pm.

  6. Foundation Update - October 2017

    ... sister/caregiver Isabella, several weeks after his stem cell transplant for severe aplastic anemia . Here's what each had to ... and Treatment; October 23, 2017; 1:00 PM EDT Don't miss these archived webinars >What is Peripheral Neuropathy? Understanding ...

    Article last updated 11/30/2017 - 2:30pm.

  7. Risk and timing of cardiovascular death among patients with myelodysplastic syndromes

    ... Author(s):  Brunner A, Blonquist T, Hobbs G, Amrein P, Neuberg D, Steensma D, Abel G, Fathi A ... syndromes (MDS) are clonal hematopoietic stem cell disorders associated with progression to leukemia and poor survival. ...

    Research Article last updated 11/03/2017 - 10:36am.

  8. Somatic HLA mutations expose the role of class I–mediated autoimmunity in aplastic anemia and its clonal complications

    ... human leukocyte antigen ( HLA )–restricted T cell immunity, with earlier studies favoring HLA class II-mediated ...

    Research Article last updated 10/23/2017 - 10:56am.

  9. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... How did the idea to study a particular type of stem cell transplant originate? The idea for the study in question is an ... are at increased risk of graft rejection. The lower T cell content and stem cell content in cord blood units likely accounted ...

    Interview last updated 10/04/2017 - 1:36pm.

  10. Pro-inflammatory proteins S100A9 and TNFα suppress erythropoietin elaboration in myelodysplastic syndromes

    ... Primary Author:  Cluzeau T Author(s):  ... has not been investigated. The HepG2 hepatoma cell line was used to investigate in vitro Epo elaboration. Serum collected ...

    Research Article last updated 10/20/2017 - 9:16am.