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  1. Aplastic Anemia and Treatment-Related Complications Influence Career Choice

    ... strep throat and a urinary tract infection just wouldn’t go away. A late-night trip to the emergency room revealed dangerously low ... search for a bone marrow donor began, because a stem cell transplantation was recommended for me. My parents and three siblings ...

    Patient Chronicle last updated 07/17/2018 - 8:20am.

  2. Isabel Mérida, PhD

    ... bone marrow by overactive immune system blood cells called T-cells. Healthy T cells are "trained" to recognize and destroy exclusively ... functions as a brake limiting immune-dependent T cell attack. We recently found that when mice are genetically modified to ...

    Grant Recipient last updated 07/05/2018 - 11:17am.

  3. Immunosuppressive Therapy

    ... works by killing specific cells in your immune system called T-lymphocytes — the cells that are attacking bone marrow stem cells ... prevents T-lymphocytes, a type of white blood cell , from becoming active. Once the T-lymphocytes are turned off by the ...

    Topic section last updated 07/06/2018 - 11:17am.

  4. Updates from John and Isabella!

    ... sister/caregiver Isabella, several weeks after his stem cell transplant for severe aplastic anemia . Here's what each had to ... and he’s up to about 6 laps right now.  So if we don’t’ make that goal, he would have to remain here longer. But becoming ...

    Patient Chronicle last updated 04/26/2018 - 12:08pm.

  5. My Encounter with Aplastic Anemia

    ... low. I had no idea what that meant at the time, and wasn’t overly alarmed. Two weeks and two different hospitals later, I was diagnosed ... T.J., had turned into hospitals, weekly red blood cell and platelet transfusions, and lots of fear. I was treated at ...

    Patient Chronicle last updated 04/26/2018 - 10:16am.

  6. In Treatment at NIH

    ... (NIH) himself. He was eventually approved for a stem cell transplant as part of a new clinical trial testing the use of ... the goals that are set, and let our team know if he isn’t. But they say that he’s coming along well!" Slow but mostly steady ...

    Patient Chronicle last updated 06/06/2018 - 10:03am.

  7. Family’s Support Spurs Recovery

    ... (Barnett and Nelda Brown) in La Place, Louisiana. He wasn’t feeling well, so I convinced him to go to urgent care before leaving to ... delivered to Jordan’s house.  With his white blood cell counts down, his house had to be sterile, and his contact with other ...

    Patient Chronicle last updated 04/26/2018 - 12:45pm.

  8. An Unusual Route to Diagnosis

    ... , hematocrit , and my red and white blood cell count. She ran several tests, and I had a liver biopsy.  After a ... with theirs.   My daughter, Sara, decided she couldn't wait to see if they were a donor match and started the process with DKMS to ...

    Patient Chronicle last updated 04/26/2018 - 12:12pm.

  9. South African Girl with PRCA Gets German Match

    ... rare bone marrow failure condition known as pure red cell aplasia (PRCA) . Her bone marrow has gone on strike and she’s not ... 10 days. She will have no immunity, and if her body doesn’t reject the new marrow and there are no infections, she will be in the ...

    Patient Chronicle last updated 04/26/2018 - 10:02am.

  10. MDS - Basics

    ... ? Bone marrow failure occurs when the marrow doesn't produce enough red cells, white cells or platelets, or the blood cells that ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia ...

    Topic section last updated 06/12/2018 - 12:47pm.