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  1. Autoreactive T Cells From Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Specifically Recognize Glycosyl- Phosphatidyl-Inositol (GPI)

    ... PNH seems to be a different type of disease. Here the PNH cell is not attacked because of a molecule it has, but rather, because of ... proteins (such as CD55 and CD59) normally prevent the red cell from being broken down by complement proteins. In a way, PNH could also be ...

    Research Review last updated 05/02/2016 - 9:26am.

  2. Association between donor leukocyte telomere length and survival after unrelated allogeneic hematopoietic cell transplantation for severe aplastic anemia

    ... Author(s):  Gadalla SM, Wang T, Haagenson M, Spellman SR, Lee SJ, Williams KM, Wong JY, De Vivo I, Savage SA ... after unrelated donor allogeneic hematopoietic cell transplantation (HCT) for patients with severe aplastic anemia . ...

    Research Article last updated 03/03/2015 - 11:48am.

  3. KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

    ... (MDS) undergoing allogeneic hematopoietic cell transplantation (HCT). The relationship of KIR2DL1 polymorphisms to ... TCR alpha-beta-Biotin system Graft ex vivo depleted of T cell receptor (TCR) αβ+CD3+/CD19+ cells ...

    Clinical Trial last updated 04/29/2016 - 2:01pm.

  4. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... Malignant conditions for which CD34+ selected, T-cell depleted allogeneic hematopoietic stem cell transplantation is indicated ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  5. UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    ... high risk CR1 as evidenced by high risk cytogenetics (e.g. t(9;22), t(1;19),t(4;11), other mixed-lineage leukemia (MLL) rearrangements, ... lymphoma in CR2 or subsequent CR Natural killer cell malignancies Chronic myelogenous leukemia (CML): all types except ...

    Clinical Trial last updated 04/29/2016 - 10:06am.

  6. Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

    ... Procedure: Allogeneic Hematopoietic Stem Cell Transplantation Undergo umbilical cord blood transplant Other Names: allogeneic stem cell transplantation HSC HSCT Drug: Cyclophosphamide Given IV Other ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ...

    Clinical Trial last updated 04/28/2016 - 1:52pm.

  7. Abatacept Reduced Intensity for Non-Malignant Diseases (Aba NMD)

    ... Allogeneic hematopoietic stem cell transplantation (HSCT) represents the only viable cure for children who ... from graft versus host disease (GVHD), driven by donor T cells recognizing and reacting against disparate host antigens. This trial is ...

    Clinical Trial last updated 04/27/2016 - 2:40pm.

  8. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... safety of nonmyeloablative conditioning and hematopoietic cell transplantation (HCT) from human leukocyte antigen ( HLA ... chimerism (> 5% cluster of differentiation [CD]3+ donor T-cell chimerism) in patients with nonmalignant inherited disorders. II. ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  9. Diagnosis

    ... uses a number of methods to measure how many of each blood cell type are in your blood sample. An LDH test looks at the level of ... ( folic acid ). These abnormal looking cells don’t work right, and this can lead to anemia. ...

    Topic section last updated 03/10/2016 - 11:04pm.

  10. Is there a special diet I should be on that would help me feel better?

    ... the risk of side effects. If your white blood cell count is very low, your doctor may ask you to avoid certain foods ... you buy at the store Stay away from buffets Don’t eat leftovers ...

    FAQ last updated 03/15/2016 - 11:38pm.