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  1. Novel strategies to prevent relapse after allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes

    ... neoplasms after allogeneic haematopoietic stem cell transplantation (HSCT) remains one of the leading causes of death. ... namely natural killer (NK) cell enrichment and adoptive T cell transfer, are emerging. Targeted therapies including vaccinations, ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

    ... phagocytosis, the latter due to the up-regulation of cell surface calreticulin, a prophagocytic marker. Blocking calreticulin on low ... for the cytopenias, and that up-regulation of the "don't eat me" signal CD47 on MDS myeloid progenitors is an important transition ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Allogeneic stem cell transplantation using alemtuzumab-containing regimens in severe aplastic anemia.

    ... engraftment after allogeneic haemopoietic stem cell transplant (HSCT). Its associated low incidence of GVHD makes it an ... tolerance post-HSCT with the findings of stable mixed T cell chimerism with full donor myeloid chimerism and the absence of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Relapse after Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes: Analysis of Late Relapse Using Comparative Karyotype and Chromosome Genome Array Testing

    ... Yeung C, Gerds AT, Fang M, Scott BL, Flowers ME, Gooley T, Deeg HJ Original Publication ... is a major cause of failure after allogeneic hematopoietic cell transplantation (HCT) in patients with myelodysplastic syndromes ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia

    ... (SAA) who received haploidentical hematopoietic stem cell transplantation (HHCT) with in vitro T cell -depleted peripheral blood stem cells . Twelve patients with ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... Primary Author:  de Witte T Author(s):  ... BACKGROUND: Allogeneic stem cell transplantation is usually considered the only curative treatment option ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Symptoms

    ... Low Red Blood Cell Counts A low red blood cell ... seek immediate medical help if they have bleeding that can’t be stopped by usual methods, such as applying pressure to the area. ...

    Topic section last updated 07/20/2018 - 5:15pm.

  8. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    ... Author(s):  Kröger N, Zabelina T, van Biezen A, Brand R, Niederwieser D, Martino R, Lim ZY, Onida F, Schmid C, ... poor outcome, but whether the outcome after allogeneic stem cell transplantation is related to the degree of bone marrow fibrosis is ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Allogeneic stem cell transplantation for myelodysplastic syndromes: critical for cure?

    ... Primary Author:  de Witte T Author(s):  ... Allogeneic stem cell transplantation (SCT) is the treatment of choice for young patients (age ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Long-term outcome of fludarabine-based reduced intensity allogeneic hematopoietic cell transplantation for debilitating paroxysmal nocturnal hemoglobinuria

    ... P, Vasu S, Khuu H, Stroncek D, Barrett J, Young NS, Donohue T, Childs RW Original Publication ... underwent a reduced intensity allogeneic hematopoietic cell transplant (HCT). All received cyclophosphamide / fludarabine ...

    Research Article last updated 07/20/2018 - 5:15pm.